Dibucaine mitigates spreading depolarization in human neocortical slices and prevents acute dendritic injury in the ischemic rodent neocortex

Medicine & Life Sciences

• Dibucaine 100%
• Neocortex 70%
• Rodentia 52%
• Ouabain 35%
• Photons 33%
• Brain 30%
• Wounds and Injuries 30%
• Sodium Channel Blockers 22%
• Stroke 21%
• Amides 18%
• Subarachnoid Hemorrhage 16%
• Local Anesthetics 16%
• Traumatic Brain Injury 15%
• Brain Injuries 15%
• Confocal Microscopy 14%
• Ions 13%
• Ischemia 11%
• Homeostasis 11%
• Oxygen 11%
• Light 11%
• Pediatrics 10%
• Glucose 9%
• Neurons 9%
• Therapeutics 5%

Agriculture & Biology

• neocortex 86%
• rodents 52%
• brain 44%
• stroke 23%
• ouabain 22%
• photons 21%
• energy deprivation 17%
• therapeutics 16%
• sodium channels 13%
• pediatrics 13%
• transmittance 12%
• mice 12%
• ischemia 11%
• space and time 11%
• anesthetics 11%
• amides 10%
• hemorrhage 10%
• lasers 10%
• preserves 9%
• microscopy 9%
• homeostasis 9%
• neurons 8%
• image analysis 8%
• ions 7%
• oxygen 7%
• glucose 6%
• tissues 4%
• methodology 2%

Chemical Compounds

• Depolarization 70%
• Spreading 66%
• Sodium Channel Blocker 9%
• Intracranial 8%
• Ouabain 6%
• Anaesthetic 6%
• Scanning Probe Microscopy 6%
• Transmittance 5%
• Wave 4%
• Glucose 3%
• Amide 3%
• Block Like Crystal 3%
• Dioxygen 2%
• Energy 2%
• Ion 2%
• Time 1%