Differential effects of left versus right seizure focus on human hippocampal evoked responses

Kimford J. Meador, David W. Loring, Brian B. Gallagher, Don W. King, Anthony M Murro, Elaine E. Thompson, Gregory P Lee, Herman F. Flanigin, Joseph R. Smith, Jennifer Dushku, Harry Davis

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Hippocampal evoked potentials were recorded using the P3 tonal oddball paradigm in 30 patients with unilateral temporal lobe seizure focus. Spectral power of the evoked potentials was decreased on the side of seizure focus, but this reduction was much greater when the focus was on the left. The effect of left/right focus does not appear to be due to group differences in age, sex, seizure duration, or operative pathology. Remote or finer left/right structural differences or differential left/right hippocampal processing for the sequential tonal task are possible explanations.

Original languageEnglish (US)
Pages (from-to)87-91
Number of pages5
JournalInternational Journal of Neuroscience
Volume66
Issue number1-2
DOIs
StatePublished - Jan 1 1992

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Seizures
Evoked Potentials
Temporal Lobe
Pathology

Keywords

  • Epilepsy
  • Evoked potentials
  • Hippocampus

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Differential effects of left versus right seizure focus on human hippocampal evoked responses. / Meador, Kimford J.; Loring, David W.; Gallagher, Brian B.; King, Don W.; Murro, Anthony M; Thompson, Elaine E.; Lee, Gregory P; Flanigin, Herman F.; Smith, Joseph R.; Dushku, Jennifer; Davis, Harry.

In: International Journal of Neuroscience, Vol. 66, No. 1-2, 01.01.1992, p. 87-91.

Research output: Contribution to journalArticle

Meador, KJ, Loring, DW, Gallagher, BB, King, DW, Murro, AM, Thompson, EE, Lee, GP, Flanigin, HF, Smith, JR, Dushku, J & Davis, H 1992, 'Differential effects of left versus right seizure focus on human hippocampal evoked responses', International Journal of Neuroscience, vol. 66, no. 1-2, pp. 87-91. https://doi.org/10.3109/00207459208999792
Meador, Kimford J. ; Loring, David W. ; Gallagher, Brian B. ; King, Don W. ; Murro, Anthony M ; Thompson, Elaine E. ; Lee, Gregory P ; Flanigin, Herman F. ; Smith, Joseph R. ; Dushku, Jennifer ; Davis, Harry. / Differential effects of left versus right seizure focus on human hippocampal evoked responses. In: International Journal of Neuroscience. 1992 ; Vol. 66, No. 1-2. pp. 87-91.
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