Differentiation of benign from malignant breast masses by time-intensity evaluation of contrast enhanced MRI

Fred W. Flickinger, Jerry David Allison, Richard M. Sherry, John C. Wright

Research output: Contribution to journalArticle

143 Scopus citations

Abstract

Using gadolinium-DTPA enhanced MRI we analyzed the enhancement characteristics of palpable breast masses in 23 patients-10 cancers and 13 benign lesions. The most specific finding for separating benign from malignant lesions was a ratio of maximum intensity change divided by the time interval during which this first occurred. Designated ranges of this ratio were specific for benign disease and sensitive for malignancy in this small patient group. Three of eight fibroadenomas exhibited enhancement patterns indistinguishable from cancer.

Original languageEnglish (US)
Pages (from-to)617-620
Number of pages4
JournalMagnetic Resonance Imaging
Volume11
Issue number5
DOIs
StatePublished - Jan 1 1993

Keywords

  • Breast neoplasms, diagnosis
  • Gadolinium-DTPA
  • Magnetic resonance (MR), contrast enhancement

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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