Abstract
1,25-Dihydroxyvitamin D3 exerts its effects by binding to the vitamin D receptor (VDR), which regulates transcription of target genes by recruiting various coactivators. Bikle and colleagues examined the role of several coactivators in human epidermal keratinocytes and found that, although these coactivators differentially associate with the VDR in proliferating versus differentiating keratinocytes, each is required for both early and late differentiation.
Original language | English (US) |
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Pages (from-to) | 748-750 |
Number of pages | 3 |
Journal | Journal of Investigative Dermatology |
Volume | 127 |
Issue number | 4 |
DOIs |
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State | Published - Apr 2007 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Dermatology
- Cell Biology