Do Aspergillus species produce biofilm?

Pranatharthi H. Chandrasekar, Elias Kurian Manavathu

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Many microorganisms possess the innate ability for adhering to biotic and abiotic objects, and grow as benthic cells. The adhered cells produce an extracellular matrix in which the cells are embedded. The matrix-forming materials together with the cells form a biofilm often hundreds of micrometers in thickness. The biofilm provides the organism with a protective niche from the inhibitory effect of antimicrobial drugs, hence the production of biofilm is considered a survival mechanism. The pathogenic yeast Candida albicans is a well-known biofilm producer. The increasing incidence of antifungal drug resistance of bioprosthetic device infections in particular, and intravascular catheter-related infections of C. albicans is now largely attributed to biofilm formation. An intriguing question is whether the ability to produce biofilm is present in pathogenic filamentous fungi such as Aspergillus species. Mowat et al. describe the development of a simple in vitro model for studying the effects of antifungal drugs on a multicellular community of Aspergillus fumigatus.

Original languageEnglish (US)
Pages (from-to)19-21
Number of pages3
JournalFuture Microbiology
Volume3
Issue number1
DOIs
StatePublished - Feb 1 2008

Fingerprint

Aspergillus
Biofilms
Candida albicans
Fungal Drug Resistance
Catheter-Related Infections
Aspergillus fumigatus
Pharmaceutical Preparations
Extracellular Matrix
Fungi
Yeasts
Equipment and Supplies
Incidence
Infection

Keywords

  • Aspergillus fumigatus
  • Biofilm
  • Drug resistance
  • Drug susceptibility
  • Multicellular community
  • Polysaccharide matrix

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Do Aspergillus species produce biofilm? / Chandrasekar, Pranatharthi H.; Manavathu, Elias Kurian.

In: Future Microbiology, Vol. 3, No. 1, 01.02.2008, p. 19-21.

Research output: Contribution to journalArticle

Chandrasekar, PH & Manavathu, EK 2008, 'Do Aspergillus species produce biofilm?', Future Microbiology, vol. 3, no. 1, pp. 19-21. https://doi.org/10.2217/17460913.3.1.19
Chandrasekar, Pranatharthi H. ; Manavathu, Elias Kurian. / Do Aspergillus species produce biofilm?. In: Future Microbiology. 2008 ; Vol. 3, No. 1. pp. 19-21.
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