TY - JOUR
T1 - Dorsal parietal area 5 Encodes immediate reach in sequential arm movements
AU - Li, Yuhui
AU - Cui, He
PY - 2013
Y1 - 2013
N2 - To generate a coherent action sequence, it is essential to integrate all component movements beforehand, and such sequence-related information has been observed in numerous brain regions. However, this high-level sequential plan encompassing multiple motor elements in parallel ultimately must be decomposed into serial motor commands to be executed by the musculoskeletal system. In the present study, we recorded single-neuron activity from dorsal parietal area 5 (area 5d) while monkeys performed a double-reach task, and found that area 5d conveys the immediate upcoming reach, but not the subsequent movement, as opposed to the entire movement sequence being encoded as in other cortical sensorimotor areas. The elementary movement coded in area 5d suggests that unfolding of the motor sequence begins in the parietal-frontal cortex, instead of being exclusively implemented by downstream subcortical and spinal circuits.
AB - To generate a coherent action sequence, it is essential to integrate all component movements beforehand, and such sequence-related information has been observed in numerous brain regions. However, this high-level sequential plan encompassing multiple motor elements in parallel ultimately must be decomposed into serial motor commands to be executed by the musculoskeletal system. In the present study, we recorded single-neuron activity from dorsal parietal area 5 (area 5d) while monkeys performed a double-reach task, and found that area 5d conveys the immediate upcoming reach, but not the subsequent movement, as opposed to the entire movement sequence being encoded as in other cortical sensorimotor areas. The elementary movement coded in area 5d suggests that unfolding of the motor sequence begins in the parietal-frontal cortex, instead of being exclusively implemented by downstream subcortical and spinal circuits.
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U2 - 10.1523/JNEUROSCI.1162-13.2013
DO - 10.1523/JNEUROSCI.1162-13.2013
M3 - Article
C2 - 24005297
AN - SCOPUS:84883414071
SN - 0270-6474
VL - 33
SP - 14455
EP - 14465
JO - Journal of Neuroscience
JF - Journal of Neuroscience
IS - 36
ER -