Early thrombosis of the superior vena cava in a patient with a central venous catheter and carcinoma of the ampulla of vater

Robert Cannon, Malay Shah, Erin Suydam, Angela Gucwa, Talmadge Bowden, Steven B Holsten

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Superior vena cava syndrome results from obstruction of flow through the vessel either by external compression or thrombosis. External compression by intrathoracic neoplasms is the most common etiology. Thrombosis of the vessel most often occurs in the setting of indwelling catheters or pacemakers. The diagnosis is suggested by the clinical manifestations of facial and upper extremity swelling, dyspnea, and cough. It is confirmed by CT scan showing the development of collateral flow around the lesion. In this report, we present a patient who developed superior vena cava thrombosis after undergoing a short period of central venous catheterization and a Whipple procedure for adenocarcinoma of the ampulla of Vater. The endothelial damage caused by the catheter, the low-flow state induced by the large fluid shifts during the operation, and the hypercoagulable state induced by malignancy fulfill Virchow's triad for venous thrombosis. To our knowledge, this is the first reported case of superior vena cava syndrome after the Whipple procedure with symptoms appearing after a shorter period of catheterization than previously reported in the adult literature.

Original languageEnglish (US)
Pages (from-to)1195-1197
Number of pages3
JournalAmerican Surgeon
Volume74
Issue number12
StatePublished - Dec 1 2008
Externally publishedYes

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'Early thrombosis of the superior vena cava in a patient with a central venous catheter and carcinoma of the ampulla of vater'. Together they form a unique fingerprint.

  • Cite this