Effect of a collagen matrix on healing in periodontal fenestration defects in dogs.

S. Y. Choi, R. E. Nilvéus, R. D. Minutello, G. J. Zimmerman, U. M. Wikesjö

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Contralateral periodontal fenestration defects in seven beagle dogs were used to evaluate influence of a collagen matrix on periodontal wound healing. The defects (6 x 4 mm) were created through the buccal cortical plates of the maxillary canine teeth following elevation of mucoperiosteal flaps. The collagen was fitted to the defects on one side. Contralateral defects served as controls. Flaps were repositioned and sutured. Dogs were sacrificed 4 weeks after surgery and block sections including teeth and surrounding structures were prepared for histometric analysis. No meaningful differences in cementum and bone regeneration were observed between treatments. There was seemingly more bone regeneration in the apical than in the coronal aspect of the defects and significantly more cementum regeneration. Root resorption was observed in one collagen and one control defect. Ankylosis was not observed. The results suggest that the maxillary canine periodontal fenestration defect can be used as a model to evaluate factors that may enhance cementum and bone regeneration. The collagen matrix neither enhanced nor inhibited periodontal wound healing in this model.

Original languageEnglish (US)
Pages (from-to)878-882
Number of pages5
JournalJournal of Periodontology
Volume64
Issue number9
DOIs
StatePublished - Jan 1 1993

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Dental Cementum
Bone Regeneration
Collagen
Dogs
Wound Healing
Cuspid
Root Resorption
Ankylosis
Cheek
Cerebral Cortex
Canidae
Regeneration
Tooth

ASJC Scopus subject areas

  • Periodontics

Cite this

Choi, S. Y., Nilvéus, R. E., Minutello, R. D., Zimmerman, G. J., & Wikesjö, U. M. (1993). Effect of a collagen matrix on healing in periodontal fenestration defects in dogs. Journal of Periodontology, 64(9), 878-882. https://doi.org/10.1902/jop.1993.64.9.878

Effect of a collagen matrix on healing in periodontal fenestration defects in dogs. / Choi, S. Y.; Nilvéus, R. E.; Minutello, R. D.; Zimmerman, G. J.; Wikesjö, U. M.

In: Journal of Periodontology, Vol. 64, No. 9, 01.01.1993, p. 878-882.

Research output: Contribution to journalArticle

Choi, SY, Nilvéus, RE, Minutello, RD, Zimmerman, GJ & Wikesjö, UM 1993, 'Effect of a collagen matrix on healing in periodontal fenestration defects in dogs.', Journal of Periodontology, vol. 64, no. 9, pp. 878-882. https://doi.org/10.1902/jop.1993.64.9.878
Choi, S. Y. ; Nilvéus, R. E. ; Minutello, R. D. ; Zimmerman, G. J. ; Wikesjö, U. M. / Effect of a collagen matrix on healing in periodontal fenestration defects in dogs. In: Journal of Periodontology. 1993 ; Vol. 64, No. 9. pp. 878-882.
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