Effect of biomimetic remineralization on the dynamic nanomechanical properties of dentin hybrid layers

H. Ryou, L. N. Niu, L. Dai, C. R. Pucci, D. D. Arola, D. H. Pashley, F. R. Tay

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

The mineral and organic phases of mineralized dentin contribute co-operatively to its strength and toughness. This study tested the null hypothesis that there is no difference in nano-dynamic mechanical behavior (complex modulus-E* loss modulus-E″ storage modulus-E'; in GPa) of dentin hybrid layers (baseline: E*, 3.86 ± 0.24; E″, 0.23 ± 0.05; E', 3.85 ± 0.24) created by an etch-and-rinse adhesive in the presence or absence of biomimetic remineralization after in vitro aging. Using scanning probe microscopy and nano-dynamic mechanical analysis, we demonstrated that biomimetic remineralization restored the nano-dynamic mechanical behavior of heavily remineralized, resin-sparse regions of dentin hybrid layers (E*, 19.73 ± 3.85; E″, 8.75 ± 3.97; E', 16.02 ± 2.58) to those of the mineralized dentin base (E*, 19.20 ± 2.42; E″, 6.57 ± 1.96; E', 17.39 ± 2.0) [p > 0.05]. Conversely, those resin-sparse, water-rich regions degraded in the absence of biomimetic remineralization, with significant decline [p < 0.05] in their complex and storage moduli (E*, 0.83 ± 0.35; E″, 0.88 ± 0.24; E', 0.62 ± 0.32). Intrafibrillar apatite deposition preserves the integrity of resin-sparse regions of hybrid layers by restoring their nanomechanical properties to those exhibited by mineralized dentin.

Original languageEnglish (US)
Pages (from-to)1122-1128
Number of pages7
JournalJournal of Dental Research
Volume90
Issue number9
DOIs
StatePublished - Sep 1 2011

Fingerprint

Biomimetics
Dentin
Scanning Probe Microscopy
Apatites
Adhesives
Minerals
Water

Keywords

  • biomimetics
  • dentin bonding
  • dynamic mechanical behavior
  • hybrid layer
  • remineralization
  • scanning probe microscopy

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Effect of biomimetic remineralization on the dynamic nanomechanical properties of dentin hybrid layers. / Ryou, H.; Niu, L. N.; Dai, L.; Pucci, C. R.; Arola, D. D.; Pashley, D. H.; Tay, F. R.

In: Journal of Dental Research, Vol. 90, No. 9, 01.09.2011, p. 1122-1128.

Research output: Contribution to journalArticle

Ryou, H. ; Niu, L. N. ; Dai, L. ; Pucci, C. R. ; Arola, D. D. ; Pashley, D. H. ; Tay, F. R. / Effect of biomimetic remineralization on the dynamic nanomechanical properties of dentin hybrid layers. In: Journal of Dental Research. 2011 ; Vol. 90, No. 9. pp. 1122-1128.
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