Effect of marine glycosides on adenosinetriphosphatase activity

Boris A Gorshkov, I. A. Gorshkova, V. A. Stonik, G. B. Elyakov

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Abstract

Marine glycosides from the sea cucumbers Actinopyga agassizi, Holothuria atra, Bohadschia argus, Cucumaria fraudatrix, Astichopus multifidus and Thelenota ananas inhibit both Na+-K+ ATPase and Mg2+-ATPase of rat brain in vitro. The glycoside-cholesterol complex of these compounds does not influence ATPase activity. Asterosaponins from starfishes Linckia guildingi and Linckia laevigata possess a slight inhibiting effect. The triterpene glycosides from sea cucumbers are more powerful inhibitors than steroidal glycosides from starfishes.

Original languageEnglish (US)
Pages (from-to)655-658
Number of pages4
JournalToxicon
Volume20
Issue number3
DOIs
StatePublished - Jan 1 1982

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ASJC Scopus subject areas

  • Toxicology

Cite this

Gorshkov, B. A., Gorshkova, I. A., Stonik, V. A., & Elyakov, G. B. (1982). Effect of marine glycosides on adenosinetriphosphatase activity. Toxicon, 20(3), 655-658. https://doi.org/10.1016/0041-0101(82)90059-9