Effect of marine glycosides on adenosinetriphosphatase activity

Boris A Gorshkov; I. A. Gorshkova; V. A. Stonik; G. B. Elyakov

doi:10.1016/0041-0101(82)90059-9

Effect of marine glycosides on adenosinetriphosphatase activity

Boris A Gorshkov, I. A. Gorshkova, V. A. Stonik, G. B. Elyakov

Pulmonary

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Marine glycosides from the sea cucumbers Actinopyga agassizi, Holothuria atra, Bohadschia argus, Cucumaria fraudatrix, Astichopus multifidus and Thelenota ananas inhibit both Na⁺-K⁺ ATPase and Mg²⁺-ATPase of rat brain in vitro. The glycoside-cholesterol complex of these compounds does not influence ATPase activity. Asterosaponins from starfishes Linckia guildingi and Linckia laevigata possess a slight inhibiting effect. The triterpene glycosides from sea cucumbers are more powerful inhibitors than steroidal glycosides from starfishes.

Original language	English (US)
Pages (from-to)	655-658
Number of pages	4
Journal	Toxicon
Volume	20
Issue number	3
DOIs	https://doi.org/10.1016/0041-0101(82)90059-9
State	Published - 1982

ASJC Scopus subject areas

Toxicology

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10.1016/0041-0101(82)90059-9

Cite this

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title = "Effect of marine glycosides on adenosinetriphosphatase activity",

abstract = "Marine glycosides from the sea cucumbers Actinopyga agassizi, Holothuria atra, Bohadschia argus, Cucumaria fraudatrix, Astichopus multifidus and Thelenota ananas inhibit both Na+-K+ ATPase and Mg2+-ATPase of rat brain in vitro. The glycoside-cholesterol complex of these compounds does not influence ATPase activity. Asterosaponins from starfishes Linckia guildingi and Linckia laevigata possess a slight inhibiting effect. The triterpene glycosides from sea cucumbers are more powerful inhibitors than steroidal glycosides from starfishes.",

author = "Gorshkov, {Boris A} and Gorshkova, {I. A.} and Stonik, {V. A.} and Elyakov, {G. B.}",

year = "1982",

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T1 - Effect of marine glycosides on adenosinetriphosphatase activity

AU - Gorshkov, Boris A

AU - Gorshkova, I. A.

AU - Stonik, V. A.

AU - Elyakov, G. B.

PY - 1982

Y1 - 1982

N2 - Marine glycosides from the sea cucumbers Actinopyga agassizi, Holothuria atra, Bohadschia argus, Cucumaria fraudatrix, Astichopus multifidus and Thelenota ananas inhibit both Na+-K+ ATPase and Mg2+-ATPase of rat brain in vitro. The glycoside-cholesterol complex of these compounds does not influence ATPase activity. Asterosaponins from starfishes Linckia guildingi and Linckia laevigata possess a slight inhibiting effect. The triterpene glycosides from sea cucumbers are more powerful inhibitors than steroidal glycosides from starfishes.

AB - Marine glycosides from the sea cucumbers Actinopyga agassizi, Holothuria atra, Bohadschia argus, Cucumaria fraudatrix, Astichopus multifidus and Thelenota ananas inhibit both Na+-K+ ATPase and Mg2+-ATPase of rat brain in vitro. The glycoside-cholesterol complex of these compounds does not influence ATPase activity. Asterosaponins from starfishes Linckia guildingi and Linckia laevigata possess a slight inhibiting effect. The triterpene glycosides from sea cucumbers are more powerful inhibitors than steroidal glycosides from starfishes.

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DO - 10.1016/0041-0101(82)90059-9

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EP - 658

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ER -

Effect of marine glycosides on adenosinetriphosphatase activity

Abstract

ASJC Scopus subject areas

UN SDGs

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