Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: A randomized controlled clinical trial

Patricia Weidlich, Carlos Heitor C. Moreira, Tiago Fiorini, Marta L. Musskopf, José M. da Rocha, Maria Lucia R. Oppermann, Anne M. Aass, Per Gjermo, Cristiano Susin, Cassiano K. Rösing, Rui V. Oppermann

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objective: This randomized controlled clinical trial was carried out to assess the effect of comprehensive nonsurgical periodontal treatment and strict plaque control performed during pregnancy on the reduction of preterm and/or low birth weight rates (PTLBW). Material and methods: Three hundred and three women were randomly allocated to receive periodontal treatment either during pregnancy (n = 147, test group) or after delivery (n = 156, control group). During pregnancy, the control group received only one session of supragingival scaling and oral hygiene instruction. In contrast, the test group received comprehensive periodontal treatment including multiple sessions of scaling and root planing, oral hygiene instructions, and frequent maintenance visits. Results: At baseline, periodontal inflammation was observed in approximately 50% of sites and attachment loss affected <15% of sites. Compared to controls, women in the test group had significant reductions in the percentage of sites with plaque (48. 5% vs. 10. 3%, p<0. 001), gingival bleeding (23. 3% vs. 2. 5%, p<0. 001), calculus (21. 3% vs. 4. 1%, p<0. 001), bleeding on probing (38. 1% vs. 2. 6%, p<0. 001) and probing depth ≥3 mm (19. 97% vs. -2. 45%, p<0. 001). No significant differences were observed between the groups in the occurrence of PT (11. 7% vs. 9. 1%, p = 0. 57), LBW (5. 6 % vs. 4. 1%, p = 0. 59), and PTLBW (4. 15% vs. 2. 60%, p = 0. 53). Conclusions: Comprehensive periodontal treatment and strict plaque control significantly improved periodontal health; however, no reduction of PTLBW rates was observed. Thus, remaining periodontal inflammation posttreatment cannot explain the lack of effect of periodontal treatment on PTLBW. Clinical relevance: This study demonstrated that periodontal diseases may be successfully treated during pregnancy. Our results do not support a potential beneficial effect of periodontal treatment on PTLBW.

Original languageEnglish (US)
Pages (from-to)37-44
Number of pages8
JournalClinical oral investigations
Volume17
Issue number1
DOIs
StatePublished - Jan 1 2013

Fingerprint

Premature Birth
Low Birth Weight Infant
Birth Rate
Randomized Controlled Trials
Pregnancy
Oral Hygiene
Therapeutics
Dental Scaling
Root Planing
Hemorrhage
Inflammation
Control Groups
Calculi
Periodontal Diseases
Maintenance
Health

Keywords

  • Periodontal diseases
  • Periodontal treatment
  • Pregnancy complications
  • Risk factors

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Weidlich, P., Moreira, C. H. C., Fiorini, T., Musskopf, M. L., da Rocha, J. M., Oppermann, M. L. R., ... Oppermann, R. V. (2013). Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: A randomized controlled clinical trial. Clinical oral investigations, 17(1), 37-44. https://doi.org/10.1007/s00784-012-0679-3

Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight : A randomized controlled clinical trial. / Weidlich, Patricia; Moreira, Carlos Heitor C.; Fiorini, Tiago; Musskopf, Marta L.; da Rocha, José M.; Oppermann, Maria Lucia R.; Aass, Anne M.; Gjermo, Per; Susin, Cristiano; Rösing, Cassiano K.; Oppermann, Rui V.

In: Clinical oral investigations, Vol. 17, No. 1, 01.01.2013, p. 37-44.

Research output: Contribution to journalArticle

Weidlich, P, Moreira, CHC, Fiorini, T, Musskopf, ML, da Rocha, JM, Oppermann, MLR, Aass, AM, Gjermo, P, Susin, C, Rösing, CK & Oppermann, RV 2013, 'Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: A randomized controlled clinical trial', Clinical oral investigations, vol. 17, no. 1, pp. 37-44. https://doi.org/10.1007/s00784-012-0679-3
Weidlich, Patricia ; Moreira, Carlos Heitor C. ; Fiorini, Tiago ; Musskopf, Marta L. ; da Rocha, José M. ; Oppermann, Maria Lucia R. ; Aass, Anne M. ; Gjermo, Per ; Susin, Cristiano ; Rösing, Cassiano K. ; Oppermann, Rui V. / Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight : A randomized controlled clinical trial. In: Clinical oral investigations. 2013 ; Vol. 17, No. 1. pp. 37-44.
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AU - Fiorini, Tiago

AU - Musskopf, Marta L.

AU - da Rocha, José M.

AU - Oppermann, Maria Lucia R.

AU - Aass, Anne M.

AU - Gjermo, Per

AU - Susin, Cristiano

AU - Rösing, Cassiano K.

AU - Oppermann, Rui V.

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N2 - Objective: This randomized controlled clinical trial was carried out to assess the effect of comprehensive nonsurgical periodontal treatment and strict plaque control performed during pregnancy on the reduction of preterm and/or low birth weight rates (PTLBW). Material and methods: Three hundred and three women were randomly allocated to receive periodontal treatment either during pregnancy (n = 147, test group) or after delivery (n = 156, control group). During pregnancy, the control group received only one session of supragingival scaling and oral hygiene instruction. In contrast, the test group received comprehensive periodontal treatment including multiple sessions of scaling and root planing, oral hygiene instructions, and frequent maintenance visits. Results: At baseline, periodontal inflammation was observed in approximately 50% of sites and attachment loss affected <15% of sites. Compared to controls, women in the test group had significant reductions in the percentage of sites with plaque (48. 5% vs. 10. 3%, p<0. 001), gingival bleeding (23. 3% vs. 2. 5%, p<0. 001), calculus (21. 3% vs. 4. 1%, p<0. 001), bleeding on probing (38. 1% vs. 2. 6%, p<0. 001) and probing depth ≥3 mm (19. 97% vs. -2. 45%, p<0. 001). No significant differences were observed between the groups in the occurrence of PT (11. 7% vs. 9. 1%, p = 0. 57), LBW (5. 6 % vs. 4. 1%, p = 0. 59), and PTLBW (4. 15% vs. 2. 60%, p = 0. 53). Conclusions: Comprehensive periodontal treatment and strict plaque control significantly improved periodontal health; however, no reduction of PTLBW rates was observed. Thus, remaining periodontal inflammation posttreatment cannot explain the lack of effect of periodontal treatment on PTLBW. Clinical relevance: This study demonstrated that periodontal diseases may be successfully treated during pregnancy. Our results do not support a potential beneficial effect of periodontal treatment on PTLBW.

AB - Objective: This randomized controlled clinical trial was carried out to assess the effect of comprehensive nonsurgical periodontal treatment and strict plaque control performed during pregnancy on the reduction of preterm and/or low birth weight rates (PTLBW). Material and methods: Three hundred and three women were randomly allocated to receive periodontal treatment either during pregnancy (n = 147, test group) or after delivery (n = 156, control group). During pregnancy, the control group received only one session of supragingival scaling and oral hygiene instruction. In contrast, the test group received comprehensive periodontal treatment including multiple sessions of scaling and root planing, oral hygiene instructions, and frequent maintenance visits. Results: At baseline, periodontal inflammation was observed in approximately 50% of sites and attachment loss affected <15% of sites. Compared to controls, women in the test group had significant reductions in the percentage of sites with plaque (48. 5% vs. 10. 3%, p<0. 001), gingival bleeding (23. 3% vs. 2. 5%, p<0. 001), calculus (21. 3% vs. 4. 1%, p<0. 001), bleeding on probing (38. 1% vs. 2. 6%, p<0. 001) and probing depth ≥3 mm (19. 97% vs. -2. 45%, p<0. 001). No significant differences were observed between the groups in the occurrence of PT (11. 7% vs. 9. 1%, p = 0. 57), LBW (5. 6 % vs. 4. 1%, p = 0. 59), and PTLBW (4. 15% vs. 2. 60%, p = 0. 53). Conclusions: Comprehensive periodontal treatment and strict plaque control significantly improved periodontal health; however, no reduction of PTLBW rates was observed. Thus, remaining periodontal inflammation posttreatment cannot explain the lack of effect of periodontal treatment on PTLBW. Clinical relevance: This study demonstrated that periodontal diseases may be successfully treated during pregnancy. Our results do not support a potential beneficial effect of periodontal treatment on PTLBW.

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