Effect of smoking on aging of photoprotected skin: Evidence gathered using a new photonumeric scale

Yolanda R. Helfrich, Le Yu, Abena O Ofori, Ted A. Hamilton, Jennifer Lambert, Anya King, John J. Voorhees, Sewon Kang

Research output: Contribution to journalArticle

50 Scopus citations

Abstract

Objectives: To develop a reproducible photonumeric scale to assess photoprotected skin aging and to determine whether health and lifestyle factors, such as smoking, affect skin aging in photoprotected sites. Design: Using standard photographs of participants' upper inner arms, we created a 9-point photonumeric scale. Three blinded reviewers used the scale to grade the photographs. Participants answered multiple lifestyle questions. Setting: Academic outpatient dermatology clinic. Participants: Eighty-two healthy men and women aged 22 to 91 years. Interventions: A professional medical photographer took standardized photographs of each participant's upper inner arm. Participants answered standardized health and lifestyle questions. Main Outcome Measures: (1) Interobserver agreement and reproducibility using the photonumeric scale and (2) health and lifestyle factors most predictive of the degree of aging in photoprotected skin. Results: There was good blinded interobserver agreement as measured by the maximum range of disagreement scores for each participant (mean, 0.91; 95% confidence interval, 0.76-1.06). Results were reproducible. We developed a multiple regression model showing that the best model for predicting the degree of aging in photoprotected skin includes 2 variables: age and packs of cigarettes smoked per day. Conclusions: This photonumeric scale demonstrates good interobserver agreement and good reproducibility. Using this scale, the degree of aging in photoprotected skin was significantly correlated with patient age and a history of cigarette smoking. Additional studies are needed to continue garnering information regarding independent risk factors for aging of photoprotected skin.

Original languageEnglish (US)
Pages (from-to)397-402
Number of pages6
JournalArchives of Dermatology
Volume143
Issue number3
DOIs
StatePublished - Mar 1 2007

ASJC Scopus subject areas

  • Dermatology

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    Helfrich, Y. R., Yu, L., Ofori, A. O., Hamilton, T. A., Lambert, J., King, A., Voorhees, J. J., & Kang, S. (2007). Effect of smoking on aging of photoprotected skin: Evidence gathered using a new photonumeric scale. Archives of Dermatology, 143(3), 397-402. https://doi.org/10.1001/archderm.143.3.397