Effects of a low sodium diet on bone metabolism

Laura D Carbone, Karen D. Barrow, Andrew J. Bush, M. David Boatright, Jean A. Michelson, Kathleen A. Pitts, Victorina N. Pintea, Andrew H. Kang, Mitchell Aaron Watsky

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Osteoporosis is a serious public health problem, and dietary interventions may potentially be helpful in preventing this disorder. The purpose of this study was to determine the effects of a low sodium diet on bone metabolism in postmenopausal women. This was a longitudinal study to determine the effects of a low sodium (2-g/day) diet on bone. Forty postmenopausal African-American and Caucasian women were enrolled in a 2-g/day sodium diet for 6 months. Sodium and calcium excretion, bone turnover, and calcitropic hormones (intact parathyroid hormone (PTH) and 1,25 dihydroxyvitamin D) were measured before and 6 months after the intervention. In women who had baseline sodium excretions equal to or greater than the average sodium intake in the United States (>3.4g/day), the low sodium diet resulted in significant decreases in sodium excretion (P = 0.01), in calcium excretion (P = 0.01), and in a biomarker of bone turnover, aminoterminal propeptide of type I collagen (P = 0.04). However, there were no significant changes in calcitropic hormones, including intact PTH (P = 0.97) or 1,25 dihydroxyvitamin D (P = 0.49) with the low sodium diet. These findings suggest that in postmenopausal women with sodium intakes >3.4g/day, a low sodium diet may have benefits for skeletal health.

Original languageEnglish (US)
Pages (from-to)506-513
Number of pages8
JournalJournal of Bone and Mineral Metabolism
Volume23
Issue number6
DOIs
StatePublished - Nov 1 2005

Fingerprint

Sodium-Restricted Diet
Sodium
Bone and Bones
Bone Remodeling
Parathyroid Hormone
Hormones
Diet
Calcium
Insurance Benefits
Collagen Type I
African Americans
Osteoporosis
Longitudinal Studies
Public Health
Biomarkers

Keywords

  • Bone
  • Diet
  • Sodium

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine
  • Endocrinology

Cite this

Carbone, L. D., Barrow, K. D., Bush, A. J., Boatright, M. D., Michelson, J. A., Pitts, K. A., ... Watsky, M. A. (2005). Effects of a low sodium diet on bone metabolism. Journal of Bone and Mineral Metabolism, 23(6), 506-513. https://doi.org/10.1007/s00774-005-0621-8

Effects of a low sodium diet on bone metabolism. / Carbone, Laura D; Barrow, Karen D.; Bush, Andrew J.; Boatright, M. David; Michelson, Jean A.; Pitts, Kathleen A.; Pintea, Victorina N.; Kang, Andrew H.; Watsky, Mitchell Aaron.

In: Journal of Bone and Mineral Metabolism, Vol. 23, No. 6, 01.11.2005, p. 506-513.

Research output: Contribution to journalArticle

Carbone, LD, Barrow, KD, Bush, AJ, Boatright, MD, Michelson, JA, Pitts, KA, Pintea, VN, Kang, AH & Watsky, MA 2005, 'Effects of a low sodium diet on bone metabolism', Journal of Bone and Mineral Metabolism, vol. 23, no. 6, pp. 506-513. https://doi.org/10.1007/s00774-005-0621-8
Carbone LD, Barrow KD, Bush AJ, Boatright MD, Michelson JA, Pitts KA et al. Effects of a low sodium diet on bone metabolism. Journal of Bone and Mineral Metabolism. 2005 Nov 1;23(6):506-513. https://doi.org/10.1007/s00774-005-0621-8
Carbone, Laura D ; Barrow, Karen D. ; Bush, Andrew J. ; Boatright, M. David ; Michelson, Jean A. ; Pitts, Kathleen A. ; Pintea, Victorina N. ; Kang, Andrew H. ; Watsky, Mitchell Aaron. / Effects of a low sodium diet on bone metabolism. In: Journal of Bone and Mineral Metabolism. 2005 ; Vol. 23, No. 6. pp. 506-513.
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