Effects of acid-base status and fluoride on the composition of the mineral in developing enamel and dentine in the dog.

F. C. Driessens, B. Angmar-Mänsson, H. J. Heijligers, Gary M. Whitford, R. M. Verbeeck

Research output: Contribution to journalArticle


Developing molar teeth of the dog were sectioned, embedded in copper containing polymethyl methacrylate, polished and their Ca/P and Ca/Na molar ratios investigated with the electron microprobe. The teeth were obtained at 30 days from 9 pups fed regimes of different acid-base status with or without fluoride supplementation from birth to sacrifice at 30 days. No clear trends in their Ca/P or Ca/Na ratios with variation in the diet were observed. However, evaluation of the Ca/P ratio of the enamel as a function of depth revealed that this ratio was 0.80 +/- 0.15 at the mineralization front. This suggests that in enamel brushite rather than octacalcium phosphate is the precursor phase of the mineral.

Original languageEnglish (US)
Pages (from-to)225-228
Number of pages4
JournalJournal de biologie buccale
Issue number4
Publication statusPublished - Jan 1 1987
Externally publishedYes


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