Effects of fibrinogen in vivo on dentine permeability in the dog

D. H. Pashley, S. E. Galloway, F. Stewart

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Dentine permeability measurements were made each hour for 6 h in tooth cavities prepared in control dogs or dogs which had been pretreated with a purified fraction of snake venom to deplete their plasma of fibrinogen. The control dogs exhibited a progressive fall in dentine permeability (~ 50 per cent reduction in 6 h); the permeability in the fibrinogen-depleted dogs only fell 15 per cent in 6 h. The results implicate plasma proteins, particularly high molecular-weight proteins such as fibrinogen, as agents which reduce dentine permeability in vivo.

Original languageEnglish (US)
Pages (from-to)725-728
Number of pages4
JournalArchives of Oral Biology
Volume29
Issue number9
DOIs
StatePublished - 1984

Fingerprint

Dentin Permeability
Fibrinogen
Dogs
Snake Venoms
Blood Proteins
Permeability
Tooth
Molecular Weight
Proteins

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Dentistry(all)
  • Cell Biology

Cite this

Effects of fibrinogen in vivo on dentine permeability in the dog. / Pashley, D. H.; Galloway, S. E.; Stewart, F.

In: Archives of Oral Biology, Vol. 29, No. 9, 1984, p. 725-728.

Research output: Contribution to journalArticle

Pashley, D. H. ; Galloway, S. E. ; Stewart, F. / Effects of fibrinogen in vivo on dentine permeability in the dog. In: Archives of Oral Biology. 1984 ; Vol. 29, No. 9. pp. 725-728.
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