Effects of maternal hyperoxia on the biophysical assessment of fetuses with suspected intrauterine growth retardation

David A. Ruedrich, Lawrence D Devoe, Nancy Searle

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Fifty-two third-trimester fetuses with suspected intrauterine growth retardation were studied by means of a computer-assisted biophysical assessment scheme, which used maternal hyperoxia as a diagnostic probe. Biophysical data examined included percentage of time spent in breathing, mean breath rate, and percentage of time spent in body movement during a 90-minute observation: 30-minute baseline, 15-minute hyperoxia, and 45-minute posthyperoxia. Mean baseline movement in fetuses found as neonates to have intrauterine growth retardation (N = 18) was significantly lower than that of normal fetuses (N = 34). Fetal body movements and breathing movements increased significantly after hyperoxia in the intrauterine growth retardation group but not in the normal group. Increases of more than 75% over baseline for fetal breathing and more than 250% over baseline for fetal body movements yielded a sensitivity of 56%, specificity of 94%, positive predicative value of 83%, and negative predicative value of 80%. Maternal hyperoxia during biophysical testing may improve the accuracy of detecting intrauterine growth retardation.

Original languageEnglish (US)
Pages (from-to)188-192
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume161
Issue number1
DOIs
StatePublished - Jan 1 1989

Fingerprint

Hyperoxia
Fetal Growth Retardation
Fetus
Mothers
Fetal Movement
Respiration
Third Pregnancy Trimester
Observation
Sensitivity and Specificity

Keywords

  • Intrauterine growth retardation
  • fetal breathing
  • fetal movement
  • maternal hyperoxia

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Effects of maternal hyperoxia on the biophysical assessment of fetuses with suspected intrauterine growth retardation. / Ruedrich, David A.; Devoe, Lawrence D; Searle, Nancy.

In: American Journal of Obstetrics and Gynecology, Vol. 161, No. 1, 01.01.1989, p. 188-192.

Research output: Contribution to journalArticle

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