Efficacy of transrectal ultrasound-guided seminal vesicle biopsies in the detection of seminal vesicle invasion by prostate cancer

Martha Kennedy Terris, J. E. McNeal, F. S. Freiha, T. A. Stamey

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Detection of microscopic seminal vesicle invasion with prostate cancer by transrectal ultrasound-guided seminal vesicle biopsies provides a method of evaluation that is much less subjective than digital rectal examination or imaging techniques. The accuracy of seminal vesicle biopsy is analyzed in 73 patients undergoing transrectal ultrasound-guided biopsy of 145 seminal vesicles followed by radical prostatectomy. Of 133 benign seminal vesicle biopsies 11 (8.3%) were found in the surgical specimen to have cancer involving an average of 6% of the seminal vesicle area. Of 8 seminal vesicle biopsies showing cancer adjacent to seminal vesicle epithelium 100% demonstrated seminal vesicle invasion in the surgical specimen extending for an average of 19% of the seminal vesicle area. Three biopsies exhibited cancer but no seminal vesicle epithelium; only 1 (33%) of these had seminal vesicle invasion for 5% of the seminal vesicle area. One biopsy revealed normal prostate tissue. Careful placement of bilateral biopsy sites cephalad to the prostate base (not traversing any portion of the prostate gland) is recommended. Caution should be exercised when basing treatment decisions on seminal vesicle biopsies that do not reveal seminal vesicle epithelium histologically.

Original languageEnglish (US)
Pages (from-to)1035-1039
Number of pages5
JournalJournal of Urology
Volume149
Issue number5
DOIs
StatePublished - Jan 1 1993
Externally publishedYes

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Seminal Vesicles
Prostatic Neoplasms
Biopsy
Prostate
Epithelium
Digital Rectal Examination
Neoplasms
Prostatectomy

Keywords

  • biopsy
  • prostatic neoplasms
  • seminal vesicles
  • ultrasonography

ASJC Scopus subject areas

  • Urology

Cite this

Efficacy of transrectal ultrasound-guided seminal vesicle biopsies in the detection of seminal vesicle invasion by prostate cancer. / Terris, Martha Kennedy; McNeal, J. E.; Freiha, F. S.; Stamey, T. A.

In: Journal of Urology, Vol. 149, No. 5, 01.01.1993, p. 1035-1039.

Research output: Contribution to journalArticle

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