Efficient Synthesis of Pyrazinoic Acid Hybrid Conjugates

Siva S. Panda, Abdullah M. Asiri, Mohamed Elagawany, Devan D. Buchanan, Behrad Torkian, Keerthana Bathala, Sean J. Thomas, Jason E. Capito, Muhammad N. Arshad, Abeer N. Al-Romaizan

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Benzotriazole-activated pyrazinoic acid was utilized as a versatile building block for the efficient and convenient synthesis of novel hybrid conjugates of pyrazinoic acid with secondary amines via amino acid linkers in high yields.

Original languageEnglish (US)
Article numberso-2017-d0015-op
Pages (from-to)50-58
Number of pages9
JournalSynOpen
Volume1
Issue number1
DOIs
StatePublished - Mar 1 2017

Keywords

  • amino acids
  • antituberculosis
  • benzotriazole methodology
  • pyrazinamide
  • pyrazinoic acid
  • secondary amines

ASJC Scopus subject areas

  • Biomaterials
  • Materials Science (miscellaneous)
  • Catalysis
  • Organic Chemistry

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