Electrical stimulation of the human hippocampus produces verbal intrusions during memory testing

Gregory P Lee, David W. Loring, Herman F. Flanigin, Joseph R. Smith, Kimford J. Meador

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Verbal memory testing was conducted during electrical stimulation of the human hippocampus in 12 epilepsy surgery candidates with unilateral temporal lobe seizure onset. Performance was assessed during baseline, left hippocampal stimulation and right hippocampal stimulation. Verbal intrusion errors were greater during electrical stimulation of the hippocampus contralateral to the seizure focus. These findings suggest that verbal intrusions are related to memory deficits, and that patients with cerebral disease who intrude words from an earlier portion of a learning test are likely to have bilateral cerebral dysfunction.

Original languageEnglish (US)
Pages (from-to)623-627
Number of pages5
JournalNeuropsychologia
Volume26
Issue number4
DOIs
StatePublished - Jan 1 1988

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Electric Stimulation
Hippocampus
Seizures
Memory Disorders
Temporal Lobe
Epilepsy
Learning

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

Cite this

Electrical stimulation of the human hippocampus produces verbal intrusions during memory testing. / Lee, Gregory P; Loring, David W.; Flanigin, Herman F.; Smith, Joseph R.; Meador, Kimford J.

In: Neuropsychologia, Vol. 26, No. 4, 01.01.1988, p. 623-627.

Research output: Contribution to journalArticle

Lee, Gregory P ; Loring, David W. ; Flanigin, Herman F. ; Smith, Joseph R. ; Meador, Kimford J. / Electrical stimulation of the human hippocampus produces verbal intrusions during memory testing. In: Neuropsychologia. 1988 ; Vol. 26, No. 4. pp. 623-627.
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