Abstract
Objective: To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia. Design: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia. Setting: Private Infertility clinic. Patient(s): None, charts review. Intervention(s): None, charts review. Main Outcome Measure(s): Clinical pregnancy rate (PR), implantation rate. Result(s): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases. Conclusion(s): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 606-611 |
| Number of pages | 6 |
| Journal | Fertility and Sterility |
| Volume | 86 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 1 2006 |
| Externally published | Yes |
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Keywords
- Obstructive azoospermia
- PESA
- TESA
- fertilization rate
- miscarriage
- pregnancy rate
ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia. / Dozortsev, Dmitri; Neme, Rosa; Diamond, Michael Peter; Abdelmassih, Soraya; Abdelmassih, Vicente; Oliveira, Flavio; Abdelmassih, Roger.
In: Fertility and Sterility, Vol. 86, No. 3, 01.09.2006, p. 606-611.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia
AU - Dozortsev, Dmitri
AU - Neme, Rosa
AU - Diamond, Michael Peter
AU - Abdelmassih, Soraya
AU - Abdelmassih, Vicente
AU - Oliveira, Flavio
AU - Abdelmassih, Roger
PY - 2006/9/1
Y1 - 2006/9/1
N2 - Objective: To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia. Design: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia. Setting: Private Infertility clinic. Patient(s): None, charts review. Intervention(s): None, charts review. Main Outcome Measure(s): Clinical pregnancy rate (PR), implantation rate. Result(s): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases. Conclusion(s): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.
AB - Objective: To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia. Design: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia. Setting: Private Infertility clinic. Patient(s): None, charts review. Intervention(s): None, charts review. Main Outcome Measure(s): Clinical pregnancy rate (PR), implantation rate. Result(s): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases. Conclusion(s): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.
KW - Obstructive azoospermia
KW - PESA
KW - TESA
KW - fertilization rate
KW - miscarriage
KW - pregnancy rate
UR - http://www.scopus.com/inward/record.url?scp=33748113143&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33748113143&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2006.01.036
DO - 10.1016/j.fertnstert.2006.01.036
M3 - Article
C2 - 16952508
AN - SCOPUS:33748113143
VL - 86
SP - 606
EP - 611
JO - Fertility and Sterility
JF - Fertility and Sterility
SN - 0015-0282
IS - 3
ER -