Abstract
(Chemical Equation Presented) Using a chemoenzymatic synthetic strategy, (S)-imperanene and its (R)-enantiomer has been synthesized from vanillin in nine steps. The key step in the synthesis involves the use of Pseudomonas cepacia lipase (PS-30) to induce asymmetrization of the intermediary prochiral 1,3-diol in >97% ee.
Original language | English (US) |
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Pages (from-to) | 3297-3300 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 6 |
Issue number | 19 |
DOIs | |
State | Published - Sep 16 2004 |
Externally published | Yes |
ASJC Scopus subject areas
- Molecular Medicine