TY - JOUR
T1 - Endoscopic management of Cerebrospinal fluid leaks
AU - Sanderson, J. Drew
AU - Kountakis, Stilianos E.
AU - McMains, K. Christopher
PY - 2009/2
Y1 - 2009/2
N2 - Cerebrospinal fluid (CSF) rhinorrhea is an uncommon but important medical condition. It can result from trauma, intracranial hypertension, or be idiopathic in origin. If left untreated, significant sequelae can result including infectious meningitis. Beta-2 transferrin is a sensitive and specific protein marker for CSF. Various radiographic modalities have been used to localize defects, including computed tomography (CT), magnetic resonance imaging, and CT cisternography. In recent years, surgical management of this condition has evolved significantly, primarily being performed endoscopically. Reconstruction can be performed with fat, free mucosal, or fascial grafts, or with vascularized flaps. The endoscopic surgeon should have a thorough understanding of the pathophysiology and diagnosis of CSF rhinorrhea as well as several surgical options in his or her armamentarium available to treat the patient suffering from CSF rhinorrhea.
AB - Cerebrospinal fluid (CSF) rhinorrhea is an uncommon but important medical condition. It can result from trauma, intracranial hypertension, or be idiopathic in origin. If left untreated, significant sequelae can result including infectious meningitis. Beta-2 transferrin is a sensitive and specific protein marker for CSF. Various radiographic modalities have been used to localize defects, including computed tomography (CT), magnetic resonance imaging, and CT cisternography. In recent years, surgical management of this condition has evolved significantly, primarily being performed endoscopically. Reconstruction can be performed with fat, free mucosal, or fascial grafts, or with vascularized flaps. The endoscopic surgeon should have a thorough understanding of the pathophysiology and diagnosis of CSF rhinorrhea as well as several surgical options in his or her armamentarium available to treat the patient suffering from CSF rhinorrhea.
KW - Anterior skull base surgery
KW - Cerebrospinal fluid (CSF) rhinorrhea
KW - Cribriform plate
KW - Defect repair
KW - Nasal endoscopy
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U2 - 10.1055/s-0028-1112229
DO - 10.1055/s-0028-1112229
M3 - Review article
C2 - 19206026
AN - SCOPUS:60249090944
SN - 0736-6825
VL - 25
SP - 29
EP - 37
JO - Facial Plastic Surgery
JF - Facial Plastic Surgery
IS - 1
ER -