Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma

Yew Kwang Ong, C. Arturo Solares, Steve Lee, Carl H. Snyderman, Juan Fernandez-Miranda, Paul A. Gardner

Research output: Contribution to journalReview article

15 Citations (Scopus)

Abstract

Local recurrence after primary radiation of nasopharyngeal carcinoma (NPC) remains an important cause of morbidity and mortality. Salvage treatment using reirradiation or surgery has been shown to improve survival over nontreatment. Surgery is traditionally performed using an open approach. Advances in endoscopic approaches for resection of paranasal sinus tumors have been extended to NPC. This article reviews the treatment options, in particular the role of endoscopic nasopharyngectomy in the management of recurrent NPC. The endoscopic anatomy, surgical principles, and published results on endoscopic nasopharyngectomy are presented. Short-term outcomes for early-stage recurrences are promising but long-term follow-up is needed.

Original languageEnglish (US)
Pages (from-to)1141-1154
Number of pages14
JournalOtolaryngologic Clinics of North America
Volume44
Issue number5
DOIs
StatePublished - Oct 1 2011

Fingerprint

Recurrence
Salvage Therapy
Paranasal Sinuses
Anatomy
Radiation
Morbidity
Mortality
Nasopharyngeal carcinoma
Neoplasms
Therapeutics
Re-Irradiation

Keywords

  • Endoscope
  • Nasopharyngeal carcinoma
  • Nasopharyngectomy
  • Nasopharynx

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Ong, Y. K., Solares, C. A., Lee, S., Snyderman, C. H., Fernandez-Miranda, J., & Gardner, P. A. (2011). Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma. Otolaryngologic Clinics of North America, 44(5), 1141-1154. https://doi.org/10.1016/j.otc.2011.07.002

Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma. / Ong, Yew Kwang; Solares, C. Arturo; Lee, Steve; Snyderman, Carl H.; Fernandez-Miranda, Juan; Gardner, Paul A.

In: Otolaryngologic Clinics of North America, Vol. 44, No. 5, 01.10.2011, p. 1141-1154.

Research output: Contribution to journalReview article

Ong, YK, Solares, CA, Lee, S, Snyderman, CH, Fernandez-Miranda, J & Gardner, PA 2011, 'Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma', Otolaryngologic Clinics of North America, vol. 44, no. 5, pp. 1141-1154. https://doi.org/10.1016/j.otc.2011.07.002
Ong, Yew Kwang ; Solares, C. Arturo ; Lee, Steve ; Snyderman, Carl H. ; Fernandez-Miranda, Juan ; Gardner, Paul A. / Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma. In: Otolaryngologic Clinics of North America. 2011 ; Vol. 44, No. 5. pp. 1141-1154.
@article{cbbb0ff1d54e4f729bdac5f3ef60652b,
title = "Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma",
abstract = "Local recurrence after primary radiation of nasopharyngeal carcinoma (NPC) remains an important cause of morbidity and mortality. Salvage treatment using reirradiation or surgery has been shown to improve survival over nontreatment. Surgery is traditionally performed using an open approach. Advances in endoscopic approaches for resection of paranasal sinus tumors have been extended to NPC. This article reviews the treatment options, in particular the role of endoscopic nasopharyngectomy in the management of recurrent NPC. The endoscopic anatomy, surgical principles, and published results on endoscopic nasopharyngectomy are presented. Short-term outcomes for early-stage recurrences are promising but long-term follow-up is needed.",
keywords = "Endoscope, Nasopharyngeal carcinoma, Nasopharyngectomy, Nasopharynx",
author = "Ong, {Yew Kwang} and Solares, {C. Arturo} and Steve Lee and Snyderman, {Carl H.} and Juan Fernandez-Miranda and Gardner, {Paul A.}",
year = "2011",
month = "10",
day = "1",
doi = "10.1016/j.otc.2011.07.002",
language = "English (US)",
volume = "44",
pages = "1141--1154",
journal = "Otolaryngologic Clinics of North America",
issn = "0030-6665",
publisher = "W.B. Saunders Ltd",
number = "5",

}

TY - JOUR

T1 - Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma

AU - Ong, Yew Kwang

AU - Solares, C. Arturo

AU - Lee, Steve

AU - Snyderman, Carl H.

AU - Fernandez-Miranda, Juan

AU - Gardner, Paul A.

PY - 2011/10/1

Y1 - 2011/10/1

N2 - Local recurrence after primary radiation of nasopharyngeal carcinoma (NPC) remains an important cause of morbidity and mortality. Salvage treatment using reirradiation or surgery has been shown to improve survival over nontreatment. Surgery is traditionally performed using an open approach. Advances in endoscopic approaches for resection of paranasal sinus tumors have been extended to NPC. This article reviews the treatment options, in particular the role of endoscopic nasopharyngectomy in the management of recurrent NPC. The endoscopic anatomy, surgical principles, and published results on endoscopic nasopharyngectomy are presented. Short-term outcomes for early-stage recurrences are promising but long-term follow-up is needed.

AB - Local recurrence after primary radiation of nasopharyngeal carcinoma (NPC) remains an important cause of morbidity and mortality. Salvage treatment using reirradiation or surgery has been shown to improve survival over nontreatment. Surgery is traditionally performed using an open approach. Advances in endoscopic approaches for resection of paranasal sinus tumors have been extended to NPC. This article reviews the treatment options, in particular the role of endoscopic nasopharyngectomy in the management of recurrent NPC. The endoscopic anatomy, surgical principles, and published results on endoscopic nasopharyngectomy are presented. Short-term outcomes for early-stage recurrences are promising but long-term follow-up is needed.

KW - Endoscope

KW - Nasopharyngeal carcinoma

KW - Nasopharyngectomy

KW - Nasopharynx

UR - http://www.scopus.com/inward/record.url?scp=80053540993&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80053540993&partnerID=8YFLogxK

U2 - 10.1016/j.otc.2011.07.002

DO - 10.1016/j.otc.2011.07.002

M3 - Review article

VL - 44

SP - 1141

EP - 1154

JO - Otolaryngologic Clinics of North America

JF - Otolaryngologic Clinics of North America

SN - 0030-6665

IS - 5

ER -