Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma

Yew Kwang Ong, C. Arturo Solares, Steve Lee, Carl H. Snyderman, Juan Fernandez-Miranda, Paul A. Gardner

Research output: Contribution to journalReview article

20 Scopus citations

Abstract

Local recurrence after primary radiation of nasopharyngeal carcinoma (NPC) remains an important cause of morbidity and mortality. Salvage treatment using reirradiation or surgery has been shown to improve survival over nontreatment. Surgery is traditionally performed using an open approach. Advances in endoscopic approaches for resection of paranasal sinus tumors have been extended to NPC. This article reviews the treatment options, in particular the role of endoscopic nasopharyngectomy in the management of recurrent NPC. The endoscopic anatomy, surgical principles, and published results on endoscopic nasopharyngectomy are presented. Short-term outcomes for early-stage recurrences are promising but long-term follow-up is needed.

Original languageEnglish (US)
Pages (from-to)1141-1154
Number of pages14
JournalOtolaryngologic Clinics of North America
Volume44
Issue number5
DOIs
StatePublished - Oct 1 2011

Keywords

  • Endoscope
  • Nasopharyngeal carcinoma
  • Nasopharyngectomy
  • Nasopharynx

ASJC Scopus subject areas

  • Otorhinolaryngology

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    Ong, Y. K., Solares, C. A., Lee, S., Snyderman, C. H., Fernandez-Miranda, J., & Gardner, P. A. (2011). Endoscopic nasopharyngectomy and its role in managing locally recurrent nasopharyngeal carcinoma. Otolaryngologic Clinics of North America, 44(5), 1141-1154. https://doi.org/10.1016/j.otc.2011.07.002