Endothelial cell injury in the human saphenous vein: A comparative study of two valvulotomes

J. C. Hager, A. S. Moideen, S. S. Chaudhry, Scott A Barman

Research output: Contribution to journalArticle

5 Scopus citations


Use of valvulotomes in non-reversed venous conduits carries the potential of venous endothelial cell injury. Earlier studies have shown that there is a significant decrease in the number of endothelial cells present in the human saphenous vein when employing the circular (LeMaitre) valvulotome. The present study was performed to evaluate and compare the LeMaitre and modified Hall valvulotome techniques on vascular endothelial cells from human saphenous vein. The results of the present study indicate that while both valvulotomes caused a significant decrease in the number of endothelial cells, the modified Hall instrument was less damaging to the vascular endothelium than the LeMaitre valvulotome. These results suggest that the modified Hall valvulotome technique may be more beneficial in maintaining endothelial cell function when the use of a valvulotome is warranted.

Original languageEnglish (US)
Pages (from-to)291-292
Number of pages2
Issue number3
StatePublished - Jan 1 1995



  • endothelial injury. Hall and LeMaitre valvulotomes
  • saphenous vein

ASJC Scopus subject areas

  • Surgery
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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