Endotoxin and sepsis research: Simplistic approaches have failed

Research output: Contribution to journalEditorial

Abstract

The sepsis syndrome has been revealed to be incredibly complex, involving many mediators that we just now are starting to appreciate. Future clinical trials of new sepsis-related therapeutic products may need to consider other endpoints in addition to mortality. Also, better identification of the subset of patients likely to benefit from these products is necessary, as are rapid diagnostic assays for endotoxin, tumor necrosis factor, and various cytokines.

Original languageEnglish (US)
Pages (from-to)653-654
Number of pages2
JournalComplications in Surgery
Volume13
Issue number5
StatePublished - Jan 1 1994
Externally publishedYes

Fingerprint

Systemic Inflammatory Response Syndrome
Endotoxins
Sepsis
Tumor Necrosis Factor-alpha
Clinical Trials
Cytokines
Mortality
Research
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Endotoxin and sepsis research : Simplistic approaches have failed. / MacArthur, Rodger David; Bone, R. C.

In: Complications in Surgery, Vol. 13, No. 5, 01.01.1994, p. 653-654.

Research output: Contribution to journalEditorial

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