Objective: To evaluate the role of epidemiologic factors in patients with polyps and asthma. Study Design: Prospective cohort Methods: Data was prospectively collected on patients presenting with chronic rhinosinusitis between 2003 and 2010. Results: The group with polyps and asthma had significantly higher Lund- Kennedy and SNOT-20 scores pre and postoperatively compared to the control group. African Americans with polyps and asthma had statistically significant improvement at 6 months. However, no significant improvement was noted at 12 months postoperatively. Discussion: In the group with nasal polyps and asthma, African Americans had poorer outcomes than Caucasians following functional endoscopic sinus surgery. There are a number of potential explanations for such findings including a genetic predisposition for more rapidly progressive disease Conclusion: This study indicates that African Americans with CRS, nasal polyps and asthma tend to have poorer response to long term treatment following functional endoscopic sinus surgery.
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