Epidemiology of immunoglobulin E levels in a defined population

M. H. Criqui, J. Seibles, R. N. Hamburger, Steven Scott Coughlin, S. Gabriel

Research output: Contribution to journalArticlepeer-review

42 Scopus citations

Abstract

Age-adjusted geometric mean IgE levels in 621 older subjects were higher in men (26.3 kU/L) than in women (19.1 kU/L) and decreased with age. The higher levels in men were largely a result of strong positive association with cigarette smoking. Among allergic conditions, a personal history of asthma was associated with the highest IgE levels. In multiple linear regression models in men, cigarette smoking was the single strongest correlate of IgE levels, while a personal history of allergy was the strongest correlate in women. Our results suggest important nonallergic as well as allergic determinants of IgE levels in populations.

Original languageEnglish (US)
Pages (from-to)308-313
Number of pages6
JournalAnnals of Allergy
Volume64
Issue number3
StatePublished - Jan 1 1990
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy

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