Epidemiology of lumbar punctures in hospitalized patients in the United States

Adrienne Vickers, John P. Donnelly, Justin Xavier Moore, Scott R. Barnum, Theresa N. Schein, Henry E. Wang

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Objectives Lumbar puncture (LP) is an important technique for assessing and treating neurological symptoms. The objective of this study was to describe the characteristics of diagnostic lumbar punctures performed on hospitalized patients in the United States. Methods We analyzed data from the 2010 National Inpatient Sample (NIS) and the National Emergency Department Survey (NEDS). We included patients treated in the Emergency Department (ED) as well as those admitted to an inpatient bed through the ED. We identified patients undergoing LPs from ICD-9 procedural code 03.31 and CPT code 62270. We generated nationally weighted estimates of the total number of LPs. We also assessed patient and hospital characteristics of cases undergoing LP. Results Of an estimated 135 million hospitalizations (ED + admission, or ED only), there were an estimated 362,718 LPs (331,248-394,188), including 273,612 (251,850-295,375) among adults and 89,106 (71,870-106,342) among children (<18 years old). Of the 362,718 LPs, 136,764 (122,117-151,410) were performed in the ED without admission. The most common conditions associated with LP among children were fever of unknown origin, meningitis, seizures and other perinatal conditions. The most common conditions associated with LP among adults were headache and meningitis. Conclusions Lumbar Puncture remains an important procedure for diagnostic and therapeutic uses in United States Hospitals.

Original languageEnglish (US)
Article numbere0208622
JournalPloS one
Volume13
Issue number12
DOIs
StatePublished - Dec 2018

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

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    Vickers, A., Donnelly, J. P., Moore, J. X., Barnum, S. R., Schein, T. N., & Wang, H. E. (2018). Epidemiology of lumbar punctures in hospitalized patients in the United States. PloS one, 13(12), [e0208622]. https://doi.org/10.1371/journal.pone.0208622