Epigenetic regulation in acute kidney injury: New light in a dark area

Chengyuan Tang, Zheng Dong

Research output: Contribution to journalComment/debatepeer-review

3 Scopus citations

Abstract

Epigenetic mechanisms have been implicated in the pathogenesis of renal diseases, including acute kidney injury (AKI). Mar et al. now unravel the acetylation and methylation at histones that are associated with the transcription of key genes in AKI. Notably, histone modifications display a remarkable heterogeneity in ischemic and endotoxic AKI. Targeting epigenetic programs may offer novel strategies to protect kidneys from AKI and enhance kidney repair and recovery.

Original languageEnglish (US)
Pages (from-to)665-668
Number of pages4
JournalKidney International
Volume88
Issue number4
DOIs
StatePublished - Oct 3 2015

ASJC Scopus subject areas

  • Nephrology

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