Epigenetic regulation in acute kidney injury: New light in a dark area

Chengyuan Tang, Zheng Dong

Research output: Contribution to journalComment/debate

2 Citations (Scopus)

Abstract

Epigenetic mechanisms have been implicated in the pathogenesis of renal diseases, including acute kidney injury (AKI). Mar et al. now unravel the acetylation and methylation at histones that are associated with the transcription of key genes in AKI. Notably, histone modifications display a remarkable heterogeneity in ischemic and endotoxic AKI. Targeting epigenetic programs may offer novel strategies to protect kidneys from AKI and enhance kidney repair and recovery.

Original languageEnglish (US)
Pages (from-to)665-668
Number of pages4
JournalKidney International
Volume88
Issue number4
DOIs
StatePublished - Oct 3 2015

Fingerprint

Acute Kidney Injury
Epigenomics
Light
Kidney
Histone Code
Acetylation
Histones
Methylation
Genes

ASJC Scopus subject areas

  • Nephrology

Cite this

Epigenetic regulation in acute kidney injury : New light in a dark area. / Tang, Chengyuan; Dong, Zheng.

In: Kidney International, Vol. 88, No. 4, 03.10.2015, p. 665-668.

Research output: Contribution to journalComment/debate

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