Evaluating potentially modifiable risk factors for prevalent and incident nocturia in older adults

Theodore M. Johnson, Richard W. Sattin, Patricia Parmelee, Nancy H. Fultz, Joseph G. Ouslander

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

OBJECTIVES: To examine associations between nocturia and potentially modifiable risk factors in older adults. DESIGN: Secondary analysis of cross-sectional and longitudinal data. SETTING: Respondents were selected using population-based sampling, drawing from a single Michigan county in 1983. They were followed through 1990. PARTICIPANTS: Community-living adults aged 60 and older. MEASUREMENTS: Episodes of nocturia, development of nocturia at 2 years after baseline survey, age, sex, hypertension, diabetes mellitus, drinking fluids before bedtime, amount of fluid intake before bedtime, diuretic use, and 24-hour coffee intake. All measures were self-reported. RESULTS: Bivariate cross-sectional analysis revealed significant associations with two or more episodes of nocturia for hypertension (odds ratio (OR) = 1.7, 95% confidence interval (CI) = 1.37-2.1), diabetes mellitus (OR = 1.51, 95% CI = 1.1-2.0), diuretic use (OR = 1.7, 95% CI = 1.3-2.1), age (OR = 1.05 per additional year over 60, 95% 1.03-1.06), and number of cups of coffee (OR = 0.93 for each cup of coffee, 95% CI = 0.89-0.97). In multivariate analysis, hypertension (OR = 1.52, 95% CI = 1.2-1.9), diuretic use (OR = 1.3, 95% 95% CI = 1.0-1.7), and age (OR = 1.04 per additional year over 60, 95% 1.03-1.06) were independently associated with two or more nocturia episodes per night. No baseline factors predicted future development of nocturia (save for age, in one model). CONCLUSION: Hypertension, older age, and diuretic use were independently associated with two or more episodes of nocturia in cross-sectional analysis. No baseline factor was related to the development of nocturia over a 2-year interval in this sample. Nighttime fluid intake and coffee intake, practices providers commonly target in patients with nocturia, were not associated with nocturia in this population-based sample of community-living older adults.

Original languageEnglish (US)
Pages (from-to)1011-1016
Number of pages6
JournalJournal of the American Geriatrics Society
Volume53
Issue number6
DOIs
StatePublished - Jun 1 2005

Fingerprint

Nocturia
Odds Ratio
Coffee
Confidence Intervals
Diuretics
Hypertension
Cross-Sectional Studies
Diabetes Mellitus
Population
Drinking
Multivariate Analysis

Keywords

  • Aging
  • Epidemiology
  • Fluid intake
  • Hypertension
  • Nocturia

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Evaluating potentially modifiable risk factors for prevalent and incident nocturia in older adults. / Johnson, Theodore M.; Sattin, Richard W.; Parmelee, Patricia; Fultz, Nancy H.; Ouslander, Joseph G.

In: Journal of the American Geriatrics Society, Vol. 53, No. 6, 01.06.2005, p. 1011-1016.

Research output: Contribution to journalArticle

Johnson, Theodore M. ; Sattin, Richard W. ; Parmelee, Patricia ; Fultz, Nancy H. ; Ouslander, Joseph G. / Evaluating potentially modifiable risk factors for prevalent and incident nocturia in older adults. In: Journal of the American Geriatrics Society. 2005 ; Vol. 53, No. 6. pp. 1011-1016.
@article{c93c869d85bd489385dd4f0df5ec8b4b,
title = "Evaluating potentially modifiable risk factors for prevalent and incident nocturia in older adults",
abstract = "OBJECTIVES: To examine associations between nocturia and potentially modifiable risk factors in older adults. DESIGN: Secondary analysis of cross-sectional and longitudinal data. SETTING: Respondents were selected using population-based sampling, drawing from a single Michigan county in 1983. They were followed through 1990. PARTICIPANTS: Community-living adults aged 60 and older. MEASUREMENTS: Episodes of nocturia, development of nocturia at 2 years after baseline survey, age, sex, hypertension, diabetes mellitus, drinking fluids before bedtime, amount of fluid intake before bedtime, diuretic use, and 24-hour coffee intake. All measures were self-reported. RESULTS: Bivariate cross-sectional analysis revealed significant associations with two or more episodes of nocturia for hypertension (odds ratio (OR) = 1.7, 95{\%} confidence interval (CI) = 1.37-2.1), diabetes mellitus (OR = 1.51, 95{\%} CI = 1.1-2.0), diuretic use (OR = 1.7, 95{\%} CI = 1.3-2.1), age (OR = 1.05 per additional year over 60, 95{\%} 1.03-1.06), and number of cups of coffee (OR = 0.93 for each cup of coffee, 95{\%} CI = 0.89-0.97). In multivariate analysis, hypertension (OR = 1.52, 95{\%} CI = 1.2-1.9), diuretic use (OR = 1.3, 95{\%} 95{\%} CI = 1.0-1.7), and age (OR = 1.04 per additional year over 60, 95{\%} 1.03-1.06) were independently associated with two or more nocturia episodes per night. No baseline factors predicted future development of nocturia (save for age, in one model). CONCLUSION: Hypertension, older age, and diuretic use were independently associated with two or more episodes of nocturia in cross-sectional analysis. No baseline factor was related to the development of nocturia over a 2-year interval in this sample. Nighttime fluid intake and coffee intake, practices providers commonly target in patients with nocturia, were not associated with nocturia in this population-based sample of community-living older adults.",
keywords = "Aging, Epidemiology, Fluid intake, Hypertension, Nocturia",
author = "Johnson, {Theodore M.} and Sattin, {Richard W.} and Patricia Parmelee and Fultz, {Nancy H.} and Ouslander, {Joseph G.}",
year = "2005",
month = "6",
day = "1",
doi = "10.1111/j.1532-5415.2005.53321.x",
language = "English (US)",
volume = "53",
pages = "1011--1016",
journal = "Journal of the American Geriatrics Society",
issn = "0002-8614",
publisher = "Wiley-Blackwell",
number = "6",

}

TY - JOUR

T1 - Evaluating potentially modifiable risk factors for prevalent and incident nocturia in older adults

AU - Johnson, Theodore M.

AU - Sattin, Richard W.

AU - Parmelee, Patricia

AU - Fultz, Nancy H.

AU - Ouslander, Joseph G.

PY - 2005/6/1

Y1 - 2005/6/1

N2 - OBJECTIVES: To examine associations between nocturia and potentially modifiable risk factors in older adults. DESIGN: Secondary analysis of cross-sectional and longitudinal data. SETTING: Respondents were selected using population-based sampling, drawing from a single Michigan county in 1983. They were followed through 1990. PARTICIPANTS: Community-living adults aged 60 and older. MEASUREMENTS: Episodes of nocturia, development of nocturia at 2 years after baseline survey, age, sex, hypertension, diabetes mellitus, drinking fluids before bedtime, amount of fluid intake before bedtime, diuretic use, and 24-hour coffee intake. All measures were self-reported. RESULTS: Bivariate cross-sectional analysis revealed significant associations with two or more episodes of nocturia for hypertension (odds ratio (OR) = 1.7, 95% confidence interval (CI) = 1.37-2.1), diabetes mellitus (OR = 1.51, 95% CI = 1.1-2.0), diuretic use (OR = 1.7, 95% CI = 1.3-2.1), age (OR = 1.05 per additional year over 60, 95% 1.03-1.06), and number of cups of coffee (OR = 0.93 for each cup of coffee, 95% CI = 0.89-0.97). In multivariate analysis, hypertension (OR = 1.52, 95% CI = 1.2-1.9), diuretic use (OR = 1.3, 95% 95% CI = 1.0-1.7), and age (OR = 1.04 per additional year over 60, 95% 1.03-1.06) were independently associated with two or more nocturia episodes per night. No baseline factors predicted future development of nocturia (save for age, in one model). CONCLUSION: Hypertension, older age, and diuretic use were independently associated with two or more episodes of nocturia in cross-sectional analysis. No baseline factor was related to the development of nocturia over a 2-year interval in this sample. Nighttime fluid intake and coffee intake, practices providers commonly target in patients with nocturia, were not associated with nocturia in this population-based sample of community-living older adults.

AB - OBJECTIVES: To examine associations between nocturia and potentially modifiable risk factors in older adults. DESIGN: Secondary analysis of cross-sectional and longitudinal data. SETTING: Respondents were selected using population-based sampling, drawing from a single Michigan county in 1983. They were followed through 1990. PARTICIPANTS: Community-living adults aged 60 and older. MEASUREMENTS: Episodes of nocturia, development of nocturia at 2 years after baseline survey, age, sex, hypertension, diabetes mellitus, drinking fluids before bedtime, amount of fluid intake before bedtime, diuretic use, and 24-hour coffee intake. All measures were self-reported. RESULTS: Bivariate cross-sectional analysis revealed significant associations with two or more episodes of nocturia for hypertension (odds ratio (OR) = 1.7, 95% confidence interval (CI) = 1.37-2.1), diabetes mellitus (OR = 1.51, 95% CI = 1.1-2.0), diuretic use (OR = 1.7, 95% CI = 1.3-2.1), age (OR = 1.05 per additional year over 60, 95% 1.03-1.06), and number of cups of coffee (OR = 0.93 for each cup of coffee, 95% CI = 0.89-0.97). In multivariate analysis, hypertension (OR = 1.52, 95% CI = 1.2-1.9), diuretic use (OR = 1.3, 95% 95% CI = 1.0-1.7), and age (OR = 1.04 per additional year over 60, 95% 1.03-1.06) were independently associated with two or more nocturia episodes per night. No baseline factors predicted future development of nocturia (save for age, in one model). CONCLUSION: Hypertension, older age, and diuretic use were independently associated with two or more episodes of nocturia in cross-sectional analysis. No baseline factor was related to the development of nocturia over a 2-year interval in this sample. Nighttime fluid intake and coffee intake, practices providers commonly target in patients with nocturia, were not associated with nocturia in this population-based sample of community-living older adults.

KW - Aging

KW - Epidemiology

KW - Fluid intake

KW - Hypertension

KW - Nocturia

UR - http://www.scopus.com/inward/record.url?scp=23444459721&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=23444459721&partnerID=8YFLogxK

U2 - 10.1111/j.1532-5415.2005.53321.x

DO - 10.1111/j.1532-5415.2005.53321.x

M3 - Article

C2 - 15935026

AN - SCOPUS:23444459721

VL - 53

SP - 1011

EP - 1016

JO - Journal of the American Geriatrics Society

JF - Journal of the American Geriatrics Society

SN - 0002-8614

IS - 6

ER -