Evaluation of cerebral arterial flow with transcranial Doppler ultrasound: Theoretical development and phantom studies

Mustapha R. Hatab, Cole A. Giller, Geoffrey D. Clarke

Research output: Contribution to journalArticle

31 Scopus citations


Blood flow information available from transcranial Doppler ultrasound is usually derived from velocity alone because no knowledge of vessel caliber is available. In cases such as vasospasm, where vessel size changes, the inference of flow from velocity becomes questionable. A computational technique was used to calculate a flow index and 2 vessel area indices based on the first and zero moments of the Doppler power spectrum. These indices were tested in a steady and pulsatile flow phantom using 6 different diameter elastic tubes. Changes in the flow index showed good agreement with changes in timed volume flow for different flow rates. The vessel caliber indices correctly predicted changes in area when different diameter tubes were examined. These indices may prove useful in clinical settings where the constancy of flow or vessel diameter between studies are in question.

Original languageEnglish (US)
Pages (from-to)1025-1031
Number of pages7
JournalUltrasound in Medicine and Biology
Issue number7
StatePublished - Sep 25 1997



  • Area index
  • Blood flow
  • Flow index
  • Signal processing
  • Transcranial Doppler ultrasound

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

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