Experimental prostatitis in nonhuman primates: I. Bacterial adherence in the urethra

J. Patrick Dilworth, Durwood E. Neal, Everett N. Fussell, James A. Roberts

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Both man and monkey possess urothelial (transitional cell) receptors for P‐fimbriae of Escherichia coli; however, the male urethra has pseudostratified columnar cells. We studied adherence using scanning electron microscopy and found that P‐fimbriae were the principal mediators of adherence to these cells as well. The monkey, therefore, should be a good model for the study of the ascending route of infection in prostatitis, the route thought to occur in man.

Original languageEnglish (US)
Pages (from-to)227-231
Number of pages5
JournalThe Prostate
Volume17
Issue number3
DOIs
StatePublished - 1990
Externally publishedYes

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Keywords

  • E. coli
  • P‐fimbriae
  • male urethra
  • pseudostratified columnar cells

ASJC Scopus subject areas

  • Oncology
  • Urology

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