Abstract
Poor sleep quality adversely affects quality of life in patients with psoriasis. However, the factors impairing sleep in these patients have not been well described. We reviewed the available literature linking sleep quality and psoriasis to elucidate factors that interfere with sleep. Pruritus, depression, pain, and obstructive sleep apnea may be likely sources of sleep impairment in patients with psoriasis. Fatigue resulting from sleep interference may also be implicated in this relationship. Pruritus, depression, and pain interfere with sleep quality by increasing nocturnal awakenings and sleep fragmentation. Obstructive sleep apnea may occur in a greater percentage of patients with psoriasis than control populations. Factors associated with psoriasis appear to have similarities in their cytokine and neuropeptide profiles. Moreover, these variables are complex and interconnected. Further study and awareness of potential factors impacting sleep in patients with psoriasis may provide new avenues for treatment of recalcitrant disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 114-123 |
| Number of pages | 10 |
| Journal | Journal of the American Academy of Dermatology |
| Volume | 63 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 2010 |
| Externally published | Yes |
Keywords
- dermatology
- itch
- psoriasis
- sleep
ASJC Scopus subject areas
- Dermatology