Abstract
The efficacy of different regimens of naproxen sodium for relief of dysmenorrhea in female adolescents was compared and the effect of other social/psychologic factors on the response to treatment tested. Following pretesting, 45 female adolescents were randomly assigned in a double-blind fashion to one of five treatment regimens and were followed up after 1, 2, and 3 months of treatment. There was a dose-related response to naproxen sodium therapy, with subjects receiving loading doses of 550 mg reporting better symptom relief than subjects receiving loading doses of 275 mg. During the first month of treatment, adolescents who reported increased life crisis events experienced greater symptom severity following naproxen therapy. Also, adolescents who reported more severe dysmenorrhea symptoms following three months of naproxen therapy had significantly lower self-concepts than adolescents who reported less symptoms following treatment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 489-493 |
| Number of pages | 5 |
| Journal | American Journal of Diseases of Children |
| Volume | 139 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 1985 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Factors Influencing Adolescents’ Responses to Regimens of Naproxen for Dysmenorrhea. / Durant, Robert H.; Jay, M. Susan; Shoffitt, Tamsen; Linder, Charles W.; Taylor, William.
In: American Journal of Diseases of Children, Vol. 139, No. 5, 01.01.1985, p. 489-493.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Factors Influencing Adolescents’ Responses to Regimens of Naproxen for Dysmenorrhea
AU - Durant, Robert H.
AU - Jay, M. Susan
AU - Shoffitt, Tamsen
AU - Linder, Charles W.
AU - Taylor, William
PY - 1985/1/1
Y1 - 1985/1/1
N2 - The efficacy of different regimens of naproxen sodium for relief of dysmenorrhea in female adolescents was compared and the effect of other social/psychologic factors on the response to treatment tested. Following pretesting, 45 female adolescents were randomly assigned in a double-blind fashion to one of five treatment regimens and were followed up after 1, 2, and 3 months of treatment. There was a dose-related response to naproxen sodium therapy, with subjects receiving loading doses of 550 mg reporting better symptom relief than subjects receiving loading doses of 275 mg. During the first month of treatment, adolescents who reported increased life crisis events experienced greater symptom severity following naproxen therapy. Also, adolescents who reported more severe dysmenorrhea symptoms following three months of naproxen therapy had significantly lower self-concepts than adolescents who reported less symptoms following treatment.
AB - The efficacy of different regimens of naproxen sodium for relief of dysmenorrhea in female adolescents was compared and the effect of other social/psychologic factors on the response to treatment tested. Following pretesting, 45 female adolescents were randomly assigned in a double-blind fashion to one of five treatment regimens and were followed up after 1, 2, and 3 months of treatment. There was a dose-related response to naproxen sodium therapy, with subjects receiving loading doses of 550 mg reporting better symptom relief than subjects receiving loading doses of 275 mg. During the first month of treatment, adolescents who reported increased life crisis events experienced greater symptom severity following naproxen therapy. Also, adolescents who reported more severe dysmenorrhea symptoms following three months of naproxen therapy had significantly lower self-concepts than adolescents who reported less symptoms following treatment.
UR - http://www.scopus.com/inward/record.url?scp=0021853474&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021853474&partnerID=8YFLogxK
U2 - 10.1001/archpedi.1985.02140070063035
DO - 10.1001/archpedi.1985.02140070063035
M3 - Article
C2 - 3984975
AN - SCOPUS:0021853474
VL - 139
SP - 489
EP - 493
JO - JAMA Pediatrics
JF - JAMA Pediatrics
SN - 2168-6203
IS - 5
ER -