Fluoride concentrations in dental plaque and saliva after the use of a fluoride dentifrice preceded by a calcium lactate rinse

Juliano P. Pessan, Cristina M. Sicca, Tatiana S. De Souza, Salete M.B. Da Silva, Gary M. Whitford, Marília A.R. Buzalaf

Research output: Contribution to journalArticle

33 Scopus citations


Plaque fluoride concentrations ([F]) are directly related to plaque calcium concentrations [Ca]. Attempts to increase plaque F uptake from dentifrices or rinses have used methods designed to increase plaque [Ca] but with inconsistent results. This double-blind, double-crossover study tested the effect of a 150 mM calcium lactate rinse used prior to brushing with placebo or fluoridated dentifrices (1030 p.p.m. as NaF) on plaque and salivary [F] and [Ca]. Sixteen children (8-10 yr of age) were randomly assigned to four different groups according to the four treatments (placebo dentifrice or fluoridated dentifrice preceded by calcium lactate or deionized water prerinses). Plaque and saliva were collected 1 and 12 h after brushing on day 7 after starting to use the dentifrices. F was determined using the electrode and Ca was determined using atomic absorption spectrometry. Plaque and salivary [Ca] were not significantly increased after use of the calcium lactate prerinse, except for plaque [Ca] 1 h after the use of the placebo dentifrice. A significant increase in salivary [F] was associated with the calcium lactate prerinse only at 1 h after the use of the fluoridated dentifrice. The the calcium lactate prerinse did not significantly affect plaque [F] under any condition.

Original languageEnglish (US)
Pages (from-to)489-493
Number of pages5
JournalEuropean Journal of Oral Sciences
Issue number6
StatePublished - Dec 1 2006



  • Calcium
  • Dental plaque
  • Fluoride
  • Saliva
  • Toothpaste

ASJC Scopus subject areas

  • Dentistry(all)

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