Four cases of patients with gastrointestinal granular cell tumors

Douglas L. Lowe, Ayaz J. Chaudhary, Jeffrey R. Lee, Sherman M. Chamberlain, Robert R. Schade, Urias Cuartas-Hoyos

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8 Scopus citations

Abstract

We present four cases of gastrointestinal granular cell tumors (GCT) with a literature review. Gastrointestinal granular cell tumors, a benign neural tumor thought to arise from Schwann cells, can occur in several areas, including the gastrointestinal tract. Studies suggest that endoscopic ultrasound and endoscopic removal is the treatment of choice for esophageal GCTs if they are small in size (<2 cm) and do not involve the muscularis propria. GCTs are malignant less than 2% of the time. Although most GCTs are benign and can be followed endoscopically without resection, the malignant potential warrants evaluation with endoscopic ultrasound for possible endoscopic or surgical resection.

Original languageEnglish (US)
Pages (from-to)298-300
Number of pages3
JournalSouthern medical journal
Volume100
Issue number3
DOIs
StatePublished - Mar 1 2007

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Keywords

  • Endoscopic ultrasound
  • Granular cell tumors
  • S-100 protein
  • Submucosal lesions

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lowe, D. L., Chaudhary, A. J., Lee, J. R., Chamberlain, S. M., Schade, R. R., & Cuartas-Hoyos, U. (2007). Four cases of patients with gastrointestinal granular cell tumors. Southern medical journal, 100(3), 298-300. https://doi.org/10.1097/SMJ.0b013e318030eeff