Fracture risk in patients with ankylosing spondylitis: A population based study

C. Cooper, L. Carbone, C. J. Michet, E. J. Atkinson, W. M. O'Fallon, L. J. Melton

Research output: Contribution to journalArticle

207 Citations (Scopus)

Abstract

Objective: To assess the risk of fractures among patients with ankylosing spondylitis (AS). Methods: A population based cohort study compared fracture incidence in an inception cohort of 158 Rochester, Minnesota residents newly diagnosed with AS between 1935 and 1989 with expected rates from the same community. Results: In 2,398 person-years of observation, there was no increase in the risk of limb fractures, but there was a pronounced Increase in the risk of thoracolumbar compression fractures (standardized morbidity ratio = 7.6; 95% CI, 4.3-12.6) among those with AS. Conclusion: These data point to the importance of measures aimed at maintaining axial skeletal status in patients with AS.

Original languageEnglish (US)
Pages (from-to)1877-1882
Number of pages6
JournalJournal of Rheumatology
Volume21
Issue number10
StatePublished - Jan 1 1994

Fingerprint

Ankylosing Spondylitis
Population
Compression Fractures
Cohort Studies
Extremities
Observation
Morbidity
Incidence

Keywords

  • Ankylosing spondylitis
  • Fracture
  • Osteoporosis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

Cite this

Cooper, C., Carbone, L., Michet, C. J., Atkinson, E. J., O'Fallon, W. M., & Melton, L. J. (1994). Fracture risk in patients with ankylosing spondylitis: A population based study. Journal of Rheumatology, 21(10), 1877-1882.

Fracture risk in patients with ankylosing spondylitis : A population based study. / Cooper, C.; Carbone, L.; Michet, C. J.; Atkinson, E. J.; O'Fallon, W. M.; Melton, L. J.

In: Journal of Rheumatology, Vol. 21, No. 10, 01.01.1994, p. 1877-1882.

Research output: Contribution to journalArticle

Cooper, C, Carbone, L, Michet, CJ, Atkinson, EJ, O'Fallon, WM & Melton, LJ 1994, 'Fracture risk in patients with ankylosing spondylitis: A population based study', Journal of Rheumatology, vol. 21, no. 10, pp. 1877-1882.
Cooper C, Carbone L, Michet CJ, Atkinson EJ, O'Fallon WM, Melton LJ. Fracture risk in patients with ankylosing spondylitis: A population based study. Journal of Rheumatology. 1994 Jan 1;21(10):1877-1882.
Cooper, C. ; Carbone, L. ; Michet, C. J. ; Atkinson, E. J. ; O'Fallon, W. M. ; Melton, L. J. / Fracture risk in patients with ankylosing spondylitis : A population based study. In: Journal of Rheumatology. 1994 ; Vol. 21, No. 10. pp. 1877-1882.
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