Abstract
The purpose of this study was to examine the bias and agreement between functional oxygen saturation (SO2) and fractional oxyhemoglobin (HbO2) using simulated quality control (QC) solutions and adult blood. Using a hemoximeter, 5 analysts performed at least 5 tests each on QC solutions with 3 different hemoglobin (Hb) levels and on adult blood samples of various oxygen saturation levels representing venous or arterial samples. Bias and the limits of agreement were determined using the technique of Bland and Altman. Using QC solutions with low, normal, and high Hb levels, the bias for SO2 against HbO2 was 20.82 0.50 (n = 66), 19.14 0.56 (n = 81), and 19.59 0.43 (n = 79), respectively, with SO2 reading consistently higher. The correlation between SO2 and HbO2 was –0.49, –0.69, and –0.68, respectively. Using adult blood, the bias for SO2 against HbO2 was 1.29 0.48 for venous samples (n = 62) and 1.9 0.19 for fully oxygenated samples (n = 36), and the correlation between SO2 and HbO2 was 1.0 and 0.68, respectively. These findings suggest that the consistency between the measurements of SO2 and HbO2 may be dependent on hemoglobin levels and oxygenation status. Thus, caution is warranted when assuming that the measurements of SO2 and HbO2 are interchangeable.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 210-221 |
| Number of pages | 12 |
| Journal | Biological Research For Nursing |
| Volume | 3 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jan 1 2002 |
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Keywords
- blood
- fractional oxygen saturation
- functional oxygen saturation
- quality control
ASJC Scopus subject areas
- Research and Theory
Cite this
Functional versus Fractional Oxygen Saturation Readings : Bias and Agreement Using Simulated Solutions and Adult Blood. / Shiao, Shyang-Yun Pamela.
In: Biological Research For Nursing, Vol. 3, No. 4, 01.01.2002, p. 210-221.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Functional versus Fractional Oxygen Saturation Readings
T2 - Bias and Agreement Using Simulated Solutions and Adult Blood
AU - Shiao, Shyang-Yun Pamela
PY - 2002/1/1
Y1 - 2002/1/1
N2 - The purpose of this study was to examine the bias and agreement between functional oxygen saturation (SO2) and fractional oxyhemoglobin (HbO2) using simulated quality control (QC) solutions and adult blood. Using a hemoximeter, 5 analysts performed at least 5 tests each on QC solutions with 3 different hemoglobin (Hb) levels and on adult blood samples of various oxygen saturation levels representing venous or arterial samples. Bias and the limits of agreement were determined using the technique of Bland and Altman. Using QC solutions with low, normal, and high Hb levels, the bias for SO2 against HbO2 was 20.82 0.50 (n = 66), 19.14 0.56 (n = 81), and 19.59 0.43 (n = 79), respectively, with SO2 reading consistently higher. The correlation between SO2 and HbO2 was –0.49, –0.69, and –0.68, respectively. Using adult blood, the bias for SO2 against HbO2 was 1.29 0.48 for venous samples (n = 62) and 1.9 0.19 for fully oxygenated samples (n = 36), and the correlation between SO2 and HbO2 was 1.0 and 0.68, respectively. These findings suggest that the consistency between the measurements of SO2 and HbO2 may be dependent on hemoglobin levels and oxygenation status. Thus, caution is warranted when assuming that the measurements of SO2 and HbO2 are interchangeable.
AB - The purpose of this study was to examine the bias and agreement between functional oxygen saturation (SO2) and fractional oxyhemoglobin (HbO2) using simulated quality control (QC) solutions and adult blood. Using a hemoximeter, 5 analysts performed at least 5 tests each on QC solutions with 3 different hemoglobin (Hb) levels and on adult blood samples of various oxygen saturation levels representing venous or arterial samples. Bias and the limits of agreement were determined using the technique of Bland and Altman. Using QC solutions with low, normal, and high Hb levels, the bias for SO2 against HbO2 was 20.82 0.50 (n = 66), 19.14 0.56 (n = 81), and 19.59 0.43 (n = 79), respectively, with SO2 reading consistently higher. The correlation between SO2 and HbO2 was –0.49, –0.69, and –0.68, respectively. Using adult blood, the bias for SO2 against HbO2 was 1.29 0.48 for venous samples (n = 62) and 1.9 0.19 for fully oxygenated samples (n = 36), and the correlation between SO2 and HbO2 was 1.0 and 0.68, respectively. These findings suggest that the consistency between the measurements of SO2 and HbO2 may be dependent on hemoglobin levels and oxygenation status. Thus, caution is warranted when assuming that the measurements of SO2 and HbO2 are interchangeable.
KW - blood
KW - fractional oxygen saturation
KW - functional oxygen saturation
KW - quality control
UR - http://www.scopus.com/inward/record.url?scp=0036527618&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036527618&partnerID=8YFLogxK
U2 - 10.1177/10900402003004006
DO - 10.1177/10900402003004006
M3 - Article
VL - 3
SP - 210
EP - 221
JO - Biological Research for Nursing
JF - Biological Research for Nursing
SN - 1099-8004
IS - 4
ER -