Abstract
Gastrointestinal stromal tumor (GIST) is a rare, but potentially aggressive tumor. We present an asymptomatic 64-year-old man with an incidental 9-cm GIST that arose in the posterior mediastinum. Wide surgical excision was performed with rotation of an intercostal muscle flap to buttress a surgically created esophageal wall defect. The patient is now free of disease 26 months postoperative. This tumor is defined by the carcinogenic over-expression of KIT-protein, a tyrosine kinase receptor. Accurate diagnosis of gastrointestinal stromal tumor is imperative, as specific medical therapy is now available for potential control of recurrent or metastatic disease.
Original language | English (US) |
---|---|
Pages (from-to) | 1014-1016 |
Number of pages | 3 |
Journal | European Journal of Cardio-thoracic Surgery |
Volume | 22 |
Issue number | 6 |
DOIs | |
State | Published - Dec 1 2002 |
Keywords
- Esophagus
- Gastrointestinal autonomic nerve tumor (GANT)
- Gastrointestinal stromal tumor (GIST)
- KIT
- Mediastinum
ASJC Scopus subject areas
- Surgery
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine