Gastrulation Defective protease interacts with anionic components of the drosophila ovary extracellular matrix

Research output: Contribution to journalArticle

1 Scopus citations


The Drosophila proteases Gastrulation Defective and Snake function in embryonic polarity establishment and bind heparin, a surrogate for anionic species present in the extracellular matrix. Here we demonstrate binding of GD, but not Snake, to anionic species that appear to be tightly associated with a highly purified eggshell matrix.

Original languageEnglish (US)
Pages (from-to)437-443
Number of pages7
JournalProtein and Peptide Letters
Issue number4
Publication statusPublished - Apr 1 2009



  • Drosophila
  • Embryonic polarity
  • Gastrulation Defective
  • Pipe
  • Serine protease cascade
  • Snake

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry

Cite this