Genetic characterization of kanamycin resistance in Campylobacter coli

D. E. Taylor, W. Yan, L. K. Ng, E. K. Manavathu, P. Courvalin

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The restriction map of plasmid pIP1433 from Campylobacter coli BM2509, isolated in France, was constructed and the location of the kanamycin (Km) and tetracycline (Tc) resistance markers determined using probes for aphA-3 and tetO genes, respectively. These DNA probes were used to study a second Km- and Tc-resistant strain C. coli UA696, isolated in Canada. In this strain, the Km resistance determinant was located in the chromosome. Like pIP1433, the Km resistance determinant in C. coliUA696 specified a 3'-aminoglycoside phosphotransferase of type III whereas the tetO gene was located on a non-transmissible plasmid.

Original languageEnglish (US)
Pages (from-to)665-676
Number of pages12
JournalAnnales de l'Institut Pasteur. Microbiologie
Volume139
Issue number6
DOIs
StatePublished - Nov 1 1988

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Keywords

  • 3'-Aminoglycoside phosphotransferase
  • Campylobacter coli
  • DNA probe
  • Kanamycin
  • Plasmid
  • Resistance
  • Tetracycline

ASJC Scopus subject areas

  • Microbiology
  • Applied Microbiology and Biotechnology

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