Genetic Predisposition to Neurological Complications in Patients with COVID-19

on behalf of the COVID19hostgenomesv Consortium

Research output: Contribution to journalArticlepeer-review

Abstract

Several studies have identified rare and common genetic variants associated with severe COVID-19, but no study has reported genetic determinants as predisposition factors for neurological complications. In this report, we identified rare/unique structural variants (SVs) implicated in neurological functions in two individuals with neurological manifestations of COVID-19. This report highlights the possible genetic link to the neurological symptoms with COVID-19 and calls for a collective effort to study these cohorts for a possible genetic linkage.

Original languageEnglish (US)
Article number133
JournalBiomolecules
Volume13
Issue number1
DOIs
StatePublished - Jan 2023

Keywords

  • COVID-19
  • genetic predisposition
  • neurological complications
  • optical genome mapping
  • rare SVs

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

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