Genitourinary manifestations of sickle cell disease

Surafel Gebreselassie, Matthew N. Simmons, Drogo K. Montague

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Sickle cell disease is a common genetic disorder characterized by sickling of red blood cells under conditions of reduced oxygen tension. In turn, sickling leads to intravascular hemolysis and vaso-occlusive events with subsequent tissue ischemia-reperfusion injury affecting multiple organs, including the genitourinary system. Our review of the genitourinary manifestations of sickle cell disease focuses on sickle cell nephropathy, priapism, and other genitourinary complications such as papillary necrosis and renal medullary carcinoma.

Original languageEnglish (US)
Pages (from-to)679-683
Number of pages5
JournalCleveland Clinic Journal of Medicine
Issue number10
StatePublished - 2015
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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