TY - JOUR
T1 - Genitourinary manifestations of sickle cell disease
AU - Gebreselassie, Surafel
AU - Simmons, Matthew N.
AU - Montague, Drogo K.
PY - 2015
Y1 - 2015
N2 - Sickle cell disease is a common genetic disorder characterized by sickling of red blood cells under conditions of reduced oxygen tension. In turn, sickling leads to intravascular hemolysis and vaso-occlusive events with subsequent tissue ischemia-reperfusion injury affecting multiple organs, including the genitourinary system. Our review of the genitourinary manifestations of sickle cell disease focuses on sickle cell nephropathy, priapism, and other genitourinary complications such as papillary necrosis and renal medullary carcinoma.
AB - Sickle cell disease is a common genetic disorder characterized by sickling of red blood cells under conditions of reduced oxygen tension. In turn, sickling leads to intravascular hemolysis and vaso-occlusive events with subsequent tissue ischemia-reperfusion injury affecting multiple organs, including the genitourinary system. Our review of the genitourinary manifestations of sickle cell disease focuses on sickle cell nephropathy, priapism, and other genitourinary complications such as papillary necrosis and renal medullary carcinoma.
UR - http://www.scopus.com/inward/record.url?scp=84983200639&partnerID=8YFLogxK
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U2 - 10.3949/ccjm.82a.14029
DO - 10.3949/ccjm.82a.14029
M3 - Article
C2 - 26469825
AN - SCOPUS:84983200639
SN - 0891-1150
VL - 82
SP - 679
EP - 683
JO - Cleveland Clinic Journal of Medicine
JF - Cleveland Clinic Journal of Medicine
IS - 10
ER -