Abstract
Plasma cell granulomas (pseudotumors) are rare benign, tumor-like proliferations composed chiefly of plasma cells that manifest primarily in the lungs, but may occur in various anatomic locations. We report this case of a 54-year-old male who presented with an unusual maxillary anterior gingival overgrowth treated by excisional biopsy. Histological examination revealed a dense inflammatory cell infiltrate containing mainly plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. Intraoral plasma cell granuloma is exceedingly rare, although case reports documenting such lesions have been reported. This case highlights the need to biopsy unusual lesions to rule out potential neoplasms.
Original language | English (US) |
---|---|
Pages (from-to) | 1287-1290 |
Number of pages | 4 |
Journal | Journal of periodontology |
Volume | 72 |
Issue number | 9 |
DOIs | |
State | Published - Sep 1 2001 |
Externally published | Yes |
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Keywords
- Gingival hyperplasia/diagnosis
- Gingival neoplasms/diagnosis
- Granuloma
- Plasma cell
ASJC Scopus subject areas
- Periodontics
Cite this
Gingival plasma cell granuloma. / Peacock, Mark E.; Hokett, Steven D.; Hellstein, John W.; Herold, Robert W.; Matzenbacher, Scott A.; Scales, Donald K.; Cuenin, Michael F.
In: Journal of periodontology, Vol. 72, No. 9, 01.09.2001, p. 1287-1290.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gingival plasma cell granuloma
AU - Peacock, Mark E.
AU - Hokett, Steven D.
AU - Hellstein, John W.
AU - Herold, Robert W.
AU - Matzenbacher, Scott A.
AU - Scales, Donald K.
AU - Cuenin, Michael F.
PY - 2001/9/1
Y1 - 2001/9/1
N2 - Plasma cell granulomas (pseudotumors) are rare benign, tumor-like proliferations composed chiefly of plasma cells that manifest primarily in the lungs, but may occur in various anatomic locations. We report this case of a 54-year-old male who presented with an unusual maxillary anterior gingival overgrowth treated by excisional biopsy. Histological examination revealed a dense inflammatory cell infiltrate containing mainly plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. Intraoral plasma cell granuloma is exceedingly rare, although case reports documenting such lesions have been reported. This case highlights the need to biopsy unusual lesions to rule out potential neoplasms.
AB - Plasma cell granulomas (pseudotumors) are rare benign, tumor-like proliferations composed chiefly of plasma cells that manifest primarily in the lungs, but may occur in various anatomic locations. We report this case of a 54-year-old male who presented with an unusual maxillary anterior gingival overgrowth treated by excisional biopsy. Histological examination revealed a dense inflammatory cell infiltrate containing mainly plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. Intraoral plasma cell granuloma is exceedingly rare, although case reports documenting such lesions have been reported. This case highlights the need to biopsy unusual lesions to rule out potential neoplasms.
KW - Gingival hyperplasia/diagnosis
KW - Gingival neoplasms/diagnosis
KW - Granuloma
KW - Plasma cell
UR - http://www.scopus.com/inward/record.url?scp=0035465002&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035465002&partnerID=8YFLogxK
U2 - 10.1902/jop.2000.72.9.1287
DO - 10.1902/jop.2000.72.9.1287
M3 - Article
C2 - 11577964
AN - SCOPUS:0035465002
VL - 72
SP - 1287
EP - 1290
JO - Journal of Periodontology
JF - Journal of Periodontology
SN - 0022-3492
IS - 9
ER -