Glucocorticoid-induced leucine zipper (GILZ) antagonizes TNF-α inhibition of mesenchymal stem cell osteogenic differentiation

Agriculture & Biology

• mesenchymal stromal cells 98%
• leucine zipper 98%
• glucocorticoids 80%
• tumor necrosis factor-alpha 79%
• cell differentiation 75%
• mitogen-activated protein kinase 27%
• osteoblasts 19%
• bone marrow 18%
• therapeutics 13%
• osteoclasts 11%
• bone resorption 11%
• ubiquitin-protein ligase 10%
• Retroviridae 9%
• bone formation 9%
• anti-inflammatory activity 8%
• protein degradation 8%
• cytokines 7%
• inflammation 7%
• transcription factors 6%
• protein synthesis 6%
• degradation 5%
• mice 4%

Medicine & Life Sciences

• Leucine Zippers 100%
• Glucocorticoids 68%
• Mesenchymal Stem Cells 67%
• Cell Differentiation 61%
• Tumor Necrosis Factor-alpha 53%
• Osteoblasts 16%
• Sp7 Transcription Factor 15%
• Core Binding Factor Alpha 1 Subunit 14%
• Anti-Inflammatory Agents 12%
• Ubiquitin-Protein Ligases 9%
• Extracellular Signal-Regulated MAP Kinases 9%
• Retroviridae 9%
• Osteoclasts 8%
• Bone Resorption 8%
• Proteolysis 7%
• Osteogenesis 7%
• Phosphotransferases 6%
• Transcription Factors 6%
• Cytokines 5%
• Inflammation 4%
• Messenger RNA 4%
• Therapeutics 2%

Chemical Compounds

• Osteogenic 95%
• Leucine 78%
• Glucocorticoid 41%
• Antiinflammatory 20%
• Protein 13%