Green, catalyst-free synthesis of mesalazine conjugates

Mohamed A. Ibrahim; Siva S. Panda; Khalid A. Alamry; Alan R. Katritzky

doi:10.1055/s-0033-1338532

Green, catalyst-free synthesis of mesalazine conjugates

Mohamed A. Ibrahim, Siva S. Panda, Khalid A. Alamry, Alan R. Katritzky

Chemistry and Physics

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A greener protocol for the synthesis of mesalazine conjugates is reported. Mesalazine conjugates are prepared in high yields by a one-pot reaction of mesalazine and aminoacyl/peptidoylbenzotriazoles in water under microwave irradiation.

Original language	English (US)
Pages (from-to)	3255-3258
Number of pages	4
Journal	Synthesis (Germany)
Volume	45
Issue number	23
DOIs	https://doi.org/10.1055/s-0033-1338532
State	Published - 2013

Keywords

amino acid
benzotriazole methodology
green chemistry
mesalazine
prodrug

ASJC Scopus subject areas

Organic Chemistry
Catalysis

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10.1055/s-0033-1338532

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title = "Green, catalyst-free synthesis of mesalazine conjugates",

abstract = "A greener protocol for the synthesis of mesalazine conjugates is reported. Mesalazine conjugates are prepared in high yields by a one-pot reaction of mesalazine and aminoacyl/peptidoylbenzotriazoles in water under microwave irradiation.",

keywords = "amino acid, benzotriazole methodology, green chemistry, mesalazine, prodrug",

author = "Ibrahim, {Mohamed A.} and Panda, {Siva S.} and Alamry, {Khalid A.} and Katritzky, {Alan R.}",

year = "2013",

doi = "10.1055/s-0033-1338532",

language = "English (US)",

volume = "45",

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journal = "Synthesis (Germany)",

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T1 - Green, catalyst-free synthesis of mesalazine conjugates

AU - Ibrahim, Mohamed A.

AU - Panda, Siva S.

AU - Alamry, Khalid A.

AU - Katritzky, Alan R.

PY - 2013

Y1 - 2013

N2 - A greener protocol for the synthesis of mesalazine conjugates is reported. Mesalazine conjugates are prepared in high yields by a one-pot reaction of mesalazine and aminoacyl/peptidoylbenzotriazoles in water under microwave irradiation.

AB - A greener protocol for the synthesis of mesalazine conjugates is reported. Mesalazine conjugates are prepared in high yields by a one-pot reaction of mesalazine and aminoacyl/peptidoylbenzotriazoles in water under microwave irradiation.

KW - amino acid

KW - benzotriazole methodology

KW - green chemistry

KW - mesalazine

KW - prodrug

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U2 - 10.1055/s-0033-1338532

DO - 10.1055/s-0033-1338532

M3 - Article

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JO - Synthesis (Germany)

JF - Synthesis (Germany)

IS - 23

ER -

Green, catalyst-free synthesis of mesalazine conjugates

Abstract

Keywords

ASJC Scopus subject areas

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