Gynecologic disorders and menstrual cycle lightheadedness in postural tachycardia syndrome

Kiffany J. Peggs, Hovan Nguyen, Diba Enayat, Nancy R. Keller, Ayman Al-Hendy, Satish R. Raj

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Objective: To assess differences in gynecologic history and lightheadedness during menstrual cycle phases among patients with POTS and healthy control women. Methods: In a prospective, questionnaire-based study carried out at Paden Autonomic Dysfunction Center, Vanderbilt University, between April 2005 and January 2009, a custom-designed questionnaire was administered to patients with POTS (n = 65) and healthy individuals (n = 95). The results were analyzed via Fisher exact test and Mann-Whitney U test. Results: Patients with POTS reported increased lightheadedness through all phases of the menstrual cycle phases as compared with healthy controls. Both groups experienced the greatest lightheadedness during menses, and a decrease in lightheadedness during the follicular phase. Patients with POTS reported a higher incidence of gynecologic diseases as compared with healthy controls. Conclusion: The severity of lightheadedness was found to vary during the menstrual cycle, which may relate to changes in estrogen levels. Patients with POTS also reported an increase in estrogen-related gynecologic disease.

Original languageEnglish (US)
Pages (from-to)242-246
Number of pages5
JournalInternational Journal of Gynecology and Obstetrics
Volume118
Issue number3
DOIs
StatePublished - Jan 1 2012

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Postural Orthostatic Tachycardia Syndrome
Dizziness
Menstrual Cycle
Female Genital Diseases
Estrogens
Follicular Phase
Menstruation
Nonparametric Statistics
History
Incidence

Keywords

  • Aldosterone
  • Estrogen
  • Lightheadedness
  • Menstrual cycle
  • Orthostatic tachycardia

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Gynecologic disorders and menstrual cycle lightheadedness in postural tachycardia syndrome. / Peggs, Kiffany J.; Nguyen, Hovan; Enayat, Diba; Keller, Nancy R.; Al-Hendy, Ayman; Raj, Satish R.

In: International Journal of Gynecology and Obstetrics, Vol. 118, No. 3, 01.01.2012, p. 242-246.

Research output: Contribution to journalArticle

Peggs, Kiffany J. ; Nguyen, Hovan ; Enayat, Diba ; Keller, Nancy R. ; Al-Hendy, Ayman ; Raj, Satish R. / Gynecologic disorders and menstrual cycle lightheadedness in postural tachycardia syndrome. In: International Journal of Gynecology and Obstetrics. 2012 ; Vol. 118, No. 3. pp. 242-246.
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