Abstract
A slow-moving y chain variant was discovered in the cord blood of an infant born to parents of the Han nationality from Jiangsu. The variant, which migrated electrophoretically at alkaline pH between Hb A and Hb D, was characterized by an Asp→His substitution at γ 73, while residues γ75 and γ136 were occupied by Ile and Ala, respectively. As the AγT-chain was also present, this baby has two types of abnormal γchain. The variant was named Hb F-Xin-Su.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 473-479 |
| Number of pages | 7 |
| Journal | Hemoglobin |
| Volume | 11 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 1987 |
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ASJC Scopus subject areas
- Hematology
- Clinical Biochemistry
- Genetics(clinical)
- Biochemistry, medical
Cite this
HB f-xin-su or aγt73(e17)asp→his : A new slow-moving fetal hemoglobin variant. / Ma, M.; Hu, H.; Kutlar, F.; Wilson, J. B.; Huismn, T. H.J.
In: Hemoglobin, Vol. 11, No. 5, 01.01.1987, p. 473-479.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - HB f-xin-su or aγt73(e17)asp→his
T2 - A new slow-moving fetal hemoglobin variant
AU - Ma, M.
AU - Hu, H.
AU - Kutlar, F.
AU - Wilson, J. B.
AU - Huismn, T. H.J.
PY - 1987/1/1
Y1 - 1987/1/1
N2 - A slow-moving y chain variant was discovered in the cord blood of an infant born to parents of the Han nationality from Jiangsu. The variant, which migrated electrophoretically at alkaline pH between Hb A and Hb D, was characterized by an Asp→His substitution at γ 73, while residues γ75 and γ136 were occupied by Ile and Ala, respectively. As the AγT-chain was also present, this baby has two types of abnormal γchain. The variant was named Hb F-Xin-Su.
AB - A slow-moving y chain variant was discovered in the cord blood of an infant born to parents of the Han nationality from Jiangsu. The variant, which migrated electrophoretically at alkaline pH between Hb A and Hb D, was characterized by an Asp→His substitution at γ 73, while residues γ75 and γ136 were occupied by Ile and Ala, respectively. As the AγT-chain was also present, this baby has two types of abnormal γchain. The variant was named Hb F-Xin-Su.
UR - http://www.scopus.com/inward/record.url?scp=0023567947&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023567947&partnerID=8YFLogxK
U2 - 10.3109/03630268708998007
DO - 10.3109/03630268708998007
M3 - Article
C2 - 2448269
AN - SCOPUS:0023567947
VL - 11
SP - 473
EP - 479
JO - Hemoglobin
JF - Hemoglobin
SN - 0363-0269
IS - 5
ER -