HB f-xin-su or aγt73(e17)asp→his: A new slow-moving fetal hemoglobin variant

M. Ma, H. Hu, F. Kutlar, J. B. Wilson, T. H.J. Huismn

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


A slow-moving y chain variant was discovered in the cord blood of an infant born to parents of the Han nationality from Jiangsu. The variant, which migrated electrophoretically at alkaline pH between Hb A and Hb D, was characterized by an Asp→His substitution at γ 73, while residues γ75 and γ136 were occupied by Ile and Ala, respectively. As the AγT-chain was also present, this baby has two types of abnormal γchain. The variant was named Hb F-Xin-Su.

Original languageEnglish (US)
Pages (from-to)473-479
Number of pages7
Issue number5
StatePublished - 1987

ASJC Scopus subject areas

  • Hematology
  • Clinical Biochemistry
  • Genetics(clinical)
  • Biochemistry, medical


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