TY - JOUR
T1 - HB f-xin-su or aγt73(e17)asp→his
T2 - A new slow-moving fetal hemoglobin variant
AU - Ma, M.
AU - Hu, H.
AU - Kutlar, F.
AU - Wilson, J. B.
AU - Huismn, T. H.J.
PY - 1987/1/1
Y1 - 1987/1/1
N2 - A slow-moving y chain variant was discovered in the cord blood of an infant born to parents of the Han nationality from Jiangsu. The variant, which migrated electrophoretically at alkaline pH between Hb A and Hb D, was characterized by an Asp→His substitution at γ 73, while residues γ75 and γ136 were occupied by Ile and Ala, respectively. As the AγT-chain was also present, this baby has two types of abnormal γchain. The variant was named Hb F-Xin-Su.
AB - A slow-moving y chain variant was discovered in the cord blood of an infant born to parents of the Han nationality from Jiangsu. The variant, which migrated electrophoretically at alkaline pH between Hb A and Hb D, was characterized by an Asp→His substitution at γ 73, while residues γ75 and γ136 were occupied by Ile and Ala, respectively. As the AγT-chain was also present, this baby has two types of abnormal γchain. The variant was named Hb F-Xin-Su.
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U2 - 10.3109/03630268708998007
DO - 10.3109/03630268708998007
M3 - Article
C2 - 2448269
AN - SCOPUS:0023567947
VL - 11
SP - 473
EP - 479
JO - Hemoglobin
JF - Hemoglobin
SN - 0363-0269
IS - 5
ER -