Healing a broken heart with stem cells

David M. Stern, David C. Hess, Cesar V. Borlongan

Research output: Contribution to journalReview article

4 Scopus citations


We discuss here the rapid progress of stem cell therapy in myocardial infarction. In particular, we focus on the issue of transdifferentiation as a "hallmark" of the stem cell's potential to replace damaged cells of the heart. A study by Henning and colleagues in this issue of Cell Transplantation supports the alternative notion of a nontransdifferentiation- mediated protection of the heart as an equally robust mechanism underlying the therapeutic potential of stem cells.

Original languageEnglish (US)
Pages (from-to)725-727
Number of pages3
JournalCell Transplantation
Issue number7-8
StatePublished - Dec 1 2004



  • Myocardial infarction
  • Stem cell therapy
  • Therapeutic potential
  • Transdifferentiation

ASJC Scopus subject areas

  • Biomedical Engineering
  • Cell Biology
  • Transplantation

Cite this

Stern, D. M., Hess, D. C., & Borlongan, C. V. (2004). Healing a broken heart with stem cells. Cell Transplantation, 13(7-8), 725-727.