Healing a broken heart with stem cells

David M. Stern; David C. Hess; Cesar V. Borlongan

doi:10.3727/000000004783983468

Healing a broken heart with stem cells

David M. Stern, David C. Hess, Cesar V. Borlongan

Neurology

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

We discuss here the rapid progress of stem cell therapy in myocardial infarction. In particular, we focus on the issue of transdifferentiation as a "hallmark" of the stem cell's potential to replace damaged cells of the heart. A study by Henning and colleagues in this issue of Cell Transplantation supports the alternative notion of a nontransdifferentiation- mediated protection of the heart as an equally robust mechanism underlying the therapeutic potential of stem cells.

Original language	English (US)
Pages (from-to)	725-727
Number of pages	3
Journal	Cell Transplantation
Volume	13
Issue number	7-8
DOIs	https://doi.org/10.3727/000000004783983468
State	Published - 2004

Keywords

Myocardial infarction
Stem cell therapy
Therapeutic potential
Transdifferentiation

ASJC Scopus subject areas

Biomedical Engineering
Cell Biology
Transplantation

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AB - We discuss here the rapid progress of stem cell therapy in myocardial infarction. In particular, we focus on the issue of transdifferentiation as a "hallmark" of the stem cell's potential to replace damaged cells of the heart. A study by Henning and colleagues in this issue of Cell Transplantation supports the alternative notion of a nontransdifferentiation- mediated protection of the heart as an equally robust mechanism underlying the therapeutic potential of stem cells.

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KW - Transdifferentiation

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Healing a broken heart with stem cells

Abstract

Keywords

ASJC Scopus subject areas

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