Healing a broken heart with stem cells

David M. Stern; David C. Hess; Cesar V. Borlongan

doi:10.3727/000000004783983468

Healing a broken heart with stem cells

David M. Stern, David C. Hess, Cesar V. Borlongan

Neurology

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

We discuss here the rapid progress of stem cell therapy in myocardial infarction. In particular, we focus on the issue of transdifferentiation as a "hallmark" of the stem cell's potential to replace damaged cells of the heart. A study by Henning and colleagues in this issue of Cell Transplantation supports the alternative notion of a nontransdifferentiation- mediated protection of the heart as an equally robust mechanism underlying the therapeutic potential of stem cells.

Original language	English (US)
Pages (from-to)	725-727
Number of pages	3
Journal	Cell Transplantation
Volume	13
Issue number	7-8
DOIs	https://doi.org/10.3727/000000004783983468
State	Published - Jan 1 2004

Keywords

Myocardial infarction
Stem cell therapy
Therapeutic potential
Transdifferentiation

ASJC Scopus subject areas

Biomedical Engineering
Cell Biology
Transplantation

Access to Document

10.3727/000000004783983468

Cite this

@article{aac7ef8c06f44c2895a871c501577648,

title = "Healing a broken heart with stem cells",

abstract = "We discuss here the rapid progress of stem cell therapy in myocardial infarction. In particular, we focus on the issue of transdifferentiation as a {"}hallmark{"} of the stem cell's potential to replace damaged cells of the heart. A study by Henning and colleagues in this issue of Cell Transplantation supports the alternative notion of a nontransdifferentiation- mediated protection of the heart as an equally robust mechanism underlying the therapeutic potential of stem cells.",

keywords = "Myocardial infarction, Stem cell therapy, Therapeutic potential, Transdifferentiation",

author = "Stern, {David M.} and Hess, {David C.} and Borlongan, {Cesar V.}",

year = "2004",

month = jan,

day = "1",

doi = "10.3727/000000004783983468",

language = "English (US)",

volume = "13",

pages = "725--727",

journal = "Cell Transplantation",

issn = "0963-6897",

publisher = "Cognizant Communication Corporation",

number = "7-8",

}

TY - JOUR

T1 - Healing a broken heart with stem cells

AU - Stern, David M.

AU - Hess, David C.

AU - Borlongan, Cesar V.

PY - 2004/1/1

Y1 - 2004/1/1

N2 - We discuss here the rapid progress of stem cell therapy in myocardial infarction. In particular, we focus on the issue of transdifferentiation as a "hallmark" of the stem cell's potential to replace damaged cells of the heart. A study by Henning and colleagues in this issue of Cell Transplantation supports the alternative notion of a nontransdifferentiation- mediated protection of the heart as an equally robust mechanism underlying the therapeutic potential of stem cells.

AB - We discuss here the rapid progress of stem cell therapy in myocardial infarction. In particular, we focus on the issue of transdifferentiation as a "hallmark" of the stem cell's potential to replace damaged cells of the heart. A study by Henning and colleagues in this issue of Cell Transplantation supports the alternative notion of a nontransdifferentiation- mediated protection of the heart as an equally robust mechanism underlying the therapeutic potential of stem cells.

KW - Myocardial infarction

KW - Stem cell therapy

KW - Therapeutic potential

KW - Transdifferentiation

UR - http://www.scopus.com/inward/record.url?scp=14044269493&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=14044269493&partnerID=8YFLogxK

U2 - 10.3727/000000004783983468

DO - 10.3727/000000004783983468

M3 - Review article

C2 - 15690973

AN - SCOPUS:14044269493

VL - 13

SP - 725

EP - 727

JO - Cell Transplantation

JF - Cell Transplantation

SN - 0963-6897

IS - 7-8

ER -

Healing a broken heart with stem cells

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this