Health-behavior induced disease: Return of the milk-alkali syndrome

Joseph B. Caruso, Rajendrakumar M. Patel, Karan Julka, David C. Parish

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The milk-alkali syndrome is a well-documented consequence of excessive calcium and alkali intake first recognized in association with early 20th century antacid regimens. The syndrome became rare after widespread implementation of modern peptic ulcer disease therapies. With recent trends in osteoporosis therapy coupled with widely available calcium-containing supplements, the milk-alkali syndrome has reemerged as an important clinical entity. Our case illustrates a patient who self-medicated his peptic ulcer disease with a regimen resembling a common early 20th century dyspepsia regimen. When superimposed upon chronic high calcium supplementation, the patient became acutely ill from the milk-alkali syndrome. When taken to excess, or used inappropriately, medications and supplements ordinarily considered beneficial, can have harmful effects. Our case underscores the importance of obtaining a thorough medication history including use of over-the-counter supplementation.

Original languageEnglish (US)
Pages (from-to)1053-1055
Number of pages3
JournalJournal of General Internal Medicine
Volume22
Issue number7
DOIs
StatePublished - Jul 1 2007
Externally publishedYes

Fingerprint

Hypercalcemia
Calcium
Peptic Ulcer
Health
Antacids
Dyspepsia
Alkalies
Osteoporosis
Therapeutics

Keywords

  • Calcium supplementation
  • Health behavior
  • Hypercalcemia
  • Milk-alkali syndrome

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Health-behavior induced disease : Return of the milk-alkali syndrome. / Caruso, Joseph B.; Patel, Rajendrakumar M.; Julka, Karan; Parish, David C.

In: Journal of General Internal Medicine, Vol. 22, No. 7, 01.07.2007, p. 1053-1055.

Research output: Contribution to journalArticle

Caruso, Joseph B. ; Patel, Rajendrakumar M. ; Julka, Karan ; Parish, David C. / Health-behavior induced disease : Return of the milk-alkali syndrome. In: Journal of General Internal Medicine. 2007 ; Vol. 22, No. 7. pp. 1053-1055.
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